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Table 2 Genotypes in Danish patients with Crohns Disease1.

From: The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study

  Ncase Ncontrol OR (95%CI)2 OR (95%CI)3 OR (95%CI)4 P-value5
IL1 β C-31T (rs1143627)          
   TT 165 342 1.00 - 1.00 - 1.00 -  
   CT 139 342 0.84 (0.64-0.10) 0.85 (0.65-1.12) 0.86 (0.65-1.14) 0.29
   CC 32 95 0.70 (0.45-1.09) 0.71 (0.45-1.10) 0.69 (0.44-1.09) 0.11
   CT and CC 171 437 0.81 (0.63-1.05) 0.82 (0.63-1.07) 0.82 (0.63-1.07) 0.15
IL-10 C-592A (rs1800872)          
   CC 214 483 1.00 - 1.00 - 1.00 -  
   AC 114 261 0.99 (0.75-1.29) 0.98 (0.75-1.30) 1.01 (0.76-1.34) 0.97
   AA 8 35 0.52 (0.24-1.13) 0.53 (0.24-1.16) 0.54 (0.24-1.21) 0.13
   AC and AA 122 296 0.93 (0.71-1.21) 0.93 (0.71-1.22) 0.95 (0.72-1.25) 0.72
IL-10 C-819T (rs1800871)          
   CC 216 483 1.00 - 1.00 - 1.00 -  
   CT 111 259 0.96 (0.73-1.26) 0.95 (0.72-1.25) 0.97 (0.73-1.29) 0.83
   TT 9 37 0.54 (0.26-1.15) 0.55 (0.26-1.18) 0.56 (0.26-1.22) 0.14
   CT and TT 120 296 0.91 (0.69-1.18) 0.90 (0.69-1.18) 0.92 (0.70-1.21) 0.55
IL-10 G-1082A (rs1800896)          
   GG 109 238 1.00 - 1.00 - 1.00 -  
   AG 171 374 1.00 (0.75-1.33) 0.99 (0.74-1.33) 0.97 (0.72-1.32) 0.87
   AA 56 167 0.73 (0.50-1.07) 0.75 (0.51-1.10) 0.78 (0.53-1.16) 0.23
   AG and AA 227 541 0.92 (0.70-1.21) 0.92 (0.69-1.21) 0.92 (0.69-1.22) 0.56
(rs3024505)          
   CC 203 522 1.00 - 1.00 - 1.00 -  
   CT 114 235 1.25 (0.95-1.64) 1.27 (0.96-1.68) 1.31 (0.98-1.75) 0.07
   TT 19 22 2.22 (1.18-4.19) 2.60 (1.36-4.96) 2.48 (1.27-4.84) 0.01
   CT and TT 133 779 1.33 (1.02-1.73) 1.37 (1.05-1.80) 1.40 (1.06-1.85) 0.02
HO-1 A-413T (rs2071746)          
   AA 110 267 1.00 - 1.00 - 1.00 -  
   AT 165 373 1.07 (0.81-1.43) 1.06 (0.79-1.42) 1.05 (0.78-1.42) 0.75
   TT 61 139 1.07 (0.73-1.55) 1.11 (0.76-1.62) 1.04 (0.70-1.53) 0.86
   AT and TT 226 512 1.07 (0.82-1.41) 1.08 (0.82-1.42) 1.05 (0.79-1.39) 0.75
  1. 1OR = Odds Ratio, 95%CI = 95% confidence interval,
  2. 2 Crude,
  3. 3 Adjusted for age and gender,
  4. 4 Adjusted for age, gender and smoking status.
  5. 5P for the fully adjusted estimate