Ncase | Ncontrol | OR (95%CI)2 | OR (95%CI)3 | OR (95%CI)4 | P-value5 | ||||
---|---|---|---|---|---|---|---|---|---|
IL1 β C-31T (rs1143627) | |||||||||
TT | 165 | 342 | 1.00 | - | 1.00 | - | 1.00 | - | |
CT | 139 | 342 | 0.84 | (0.64-0.10) | 0.85 | (0.65-1.12) | 0.86 | (0.65-1.14) | 0.29 |
CC | 32 | 95 | 0.70 | (0.45-1.09) | 0.71 | (0.45-1.10) | 0.69 | (0.44-1.09) | 0.11 |
CT and CC | 171 | 437 | 0.81 | (0.63-1.05) | 0.82 | (0.63-1.07) | 0.82 | (0.63-1.07) | 0.15 |
IL-10 C-592A (rs1800872) | |||||||||
CC | 214 | 483 | 1.00 | - | 1.00 | - | 1.00 | - | |
AC | 114 | 261 | 0.99 | (0.75-1.29) | 0.98 | (0.75-1.30) | 1.01 | (0.76-1.34) | 0.97 |
AA | 8 | 35 | 0.52 | (0.24-1.13) | 0.53 | (0.24-1.16) | 0.54 | (0.24-1.21) | 0.13 |
AC and AA | 122 | 296 | 0.93 | (0.71-1.21) | 0.93 | (0.71-1.22) | 0.95 | (0.72-1.25) | 0.72 |
IL-10 C-819T (rs1800871) | |||||||||
CC | 216 | 483 | 1.00 | - | 1.00 | - | 1.00 | - | |
CT | 111 | 259 | 0.96 | (0.73-1.26) | 0.95 | (0.72-1.25) | 0.97 | (0.73-1.29) | 0.83 |
TT | 9 | 37 | 0.54 | (0.26-1.15) | 0.55 | (0.26-1.18) | 0.56 | (0.26-1.22) | 0.14 |
CT and TT | 120 | 296 | 0.91 | (0.69-1.18) | 0.90 | (0.69-1.18) | 0.92 | (0.70-1.21) | 0.55 |
IL-10 G-1082A (rs1800896) | |||||||||
GG | 109 | 238 | 1.00 | - | 1.00 | - | 1.00 | - | |
AG | 171 | 374 | 1.00 | (0.75-1.33) | 0.99 | (0.74-1.33) | 0.97 | (0.72-1.32) | 0.87 |
AA | 56 | 167 | 0.73 | (0.50-1.07) | 0.75 | (0.51-1.10) | 0.78 | (0.53-1.16) | 0.23 |
AG and AA | 227 | 541 | 0.92 | (0.70-1.21) | 0.92 | (0.69-1.21) | 0.92 | (0.69-1.22) | 0.56 |
(rs3024505) | |||||||||
CC | 203 | 522 | 1.00 | - | 1.00 | - | 1.00 | - | |
CT | 114 | 235 | 1.25 | (0.95-1.64) | 1.27 | (0.96-1.68) | 1.31 | (0.98-1.75) | 0.07 |
TT | 19 | 22 | 2.22 | (1.18-4.19) | 2.60 | (1.36-4.96) | 2.48 | (1.27-4.84) | 0.01 |
CT and TT | 133 | 779 | 1.33 | (1.02-1.73) | 1.37 | (1.05-1.80) | 1.40 | (1.06-1.85) | 0.02 |
HO-1 A-413T (rs2071746) | |||||||||
AA | 110 | 267 | 1.00 | - | 1.00 | - | 1.00 | - | |
AT | 165 | 373 | 1.07 | (0.81-1.43) | 1.06 | (0.79-1.42) | 1.05 | (0.78-1.42) | 0.75 |
TT | 61 | 139 | 1.07 | (0.73-1.55) | 1.11 | (0.76-1.62) | 1.04 | (0.70-1.53) | 0.86 |
AT and TT | 226 | 512 | 1.07 | (0.82-1.41) | 1.08 | (0.82-1.42) | 1.05 | (0.79-1.39) | 0.75 |