Figure 1From: Effect of BRCA2 sequence variants predicted to disrupt exonic splice enhancers on BRCA2transcripts No evidence for altered splicing of transcripts derived from an LCL generated from a BRCA2 c.8308 G > A (p.Ala2770Thr) carrier. LCLs from a carrier of BRCA2 c.8308 G > A (p.Ala2770Thr) or two BRCA2 normal LCL controls were analysed by RT-PCR using primers specific for BRCA2 exons 16 and 19. CHX indicates cycloheximide treatment, which was used to examine transcript stability, RT indicates reverse transcriptase. N indicates no template control.Back to article page