Skip to main content

Advertisement

Table 5 The comparison of association results for T60N, G-308A and G-238A between the present study and the WTCCC T2D GWAS

From: Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes

SNP OR allele ORa 95% CIa p-value WTCCC SNPb ORa 95% CIa p-value
rs1041981 (T60N) C 0.89 0.81-0.98 0.02 rs1041981 1.06 0.96-1.16 0.67
rs1800629 (G-308A) A 0.98 0.88-1.11 0.79 rs1800629 1.05 0.93-1.19 0.56
rs361525 (G-238A) G 0.98 0.81-1.19 0.85 rs3093668 (proxy for rs361525) 0.86 0.71-1.05 0.21
  1. aOR - allelic odds ratio and 95% confidence intervals; bAll three SNPs were imputed in the WTCCC data set. 58.2% of WTCCC cases and 35.3% of WTCCC controls overlapped with the samples from our study.