Skip to main content

Table 4 Transmission disequilibrium analysis of 11 TNF/LTA tag SNPs in T2D parent-offspring trios

From: Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes

SNP

Na

A1:A2b

MAFc

T:Ud

ORe

95% CI f

p value

rs928815

322

T:G

0.359

132:165

0.8

0.64-1.01

0.055

rs909253

321

C:T

0.358

157:145

1.083

0.86-1.36

0.489

rs746868

324

C:G

0.362

135:163

0.828

0.66-1.04

0.104

rs1041981 (T60N)

301

A:C

0.355

146:138

1.058

0.84-1.34

0.635

rs1800750

327

A:G

0.012

7:12

0.583

0.23-1.48

0.251

rs1800629 (G-308A)

237

G:A

0.195

73:70

1.043

0.75-1.45

0.801

rs361525 (G-238A)

324

A:G

0.055

35:35

1

0.63-1.59

1

rs3093662

321

G:A

0.079

47:44

1.068

0.71-1.61

0.753

rs3093664

321

G:A

0.086

55:43

1.279

0.86-1.91

0.225

rs3093665

324

C:A

0.023

14:12

1.167

0.54-2.52

0.694

rs3093668

321

C:G

0.045

31:22

1.409

0.82-2.43

0.216

  1. aN - number of informative trios; bA1:A2 - minor allele vs. major allele; cMAF - minor allele frequency in affected probands; dcopies of the minor allele transmitted (T) and untransmitted (U), eodds ratios (OR), f95% lower and upper confidence intervals.