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Table 4 Transmission disequilibrium analysis of 11 TNF/LTA tag SNPs in T2D parent-offspring trios

From: Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes

SNP Na A1:A2b MAFc T:Ud ORe 95% CI f p value
rs928815 322 T:G 0.359 132:165 0.8 0.64-1.01 0.055
rs909253 321 C:T 0.358 157:145 1.083 0.86-1.36 0.489
rs746868 324 C:G 0.362 135:163 0.828 0.66-1.04 0.104
rs1041981 (T60N) 301 A:C 0.355 146:138 1.058 0.84-1.34 0.635
rs1800750 327 A:G 0.012 7:12 0.583 0.23-1.48 0.251
rs1800629 (G-308A) 237 G:A 0.195 73:70 1.043 0.75-1.45 0.801
rs361525 (G-238A) 324 A:G 0.055 35:35 1 0.63-1.59 1
rs3093662 321 G:A 0.079 47:44 1.068 0.71-1.61 0.753
rs3093664 321 G:A 0.086 55:43 1.279 0.86-1.91 0.225
rs3093665 324 C:A 0.023 14:12 1.167 0.54-2.52 0.694
rs3093668 321 C:G 0.045 31:22 1.409 0.82-2.43 0.216
  1. aN - number of informative trios; bA1:A2 - minor allele vs. major allele; cMAF - minor allele frequency in affected probands; dcopies of the minor allele transmitted (T) and untransmitted (U), eodds ratios (OR), f95% lower and upper confidence intervals.