Table 2 Genotype distribution and allele frequencies of the LPL, APOA5 and APOE variants.
Gene | Variant | Reference sequence | Genotype distribution n (%) | Allele frequencies | p 1 | |||
|---|---|---|---|---|---|---|---|---|
LPL | Hind III | rs320 | H+H+ | 920 | (50.41) | H+ | 0.708 | 0.749 |
H+H- | 743 | (40.71) | H- | 0.292 | ||||
H-H- | 162 | (8.88) | ||||||
LPL | S447X | rs328 | 447SS | 1431 | (78.41) | 447S | 0.884 | 0.470 |
447SX | 364 | (19.95) | 447X | 0.116 | ||||
447XX | 30 | (1.64) | ||||||
LPL | D9N | rs1801177 | 9DD | 1768 | (96.88) | 9D | 0.984 | 0.722 |
9DN | 56 | (3.07) | 9N | 0.016 | ||||
9NN | 1 | (0.05) | ||||||
LPL | N291S | rs268 | 291NN | 1771 | (97.04) | 291N | 0.985 | 0.892 |
291NS | 54 | (2.96) | 291S | 0.015 | ||||
291SS | 0 | (0.00) | ||||||
APOA5 | S19W | rs3135506 | 19SS | 1585 | (86.85) | 19S | 0.932 | 0.982 |
19SW | 231 | (12.66) | 19W | 0.068 | ||||
WW | 9 | (0.49) | ||||||
APOA5 | -1131T/C | rs662799 | -1131TT | 1609 | (88.16) | -1131T | 0.938 | 0.479 |
-1131TC | 206 | (11.29) | -1131C | 0.062 | ||||
-1131CC | 10 | (0.55) | ||||||
APOE | C112R | rs429358 | ε2ε2 | 4 | (0.22) | ε2 | 0.057 | 0.741 |
R158C | rs7412 | ε2ε3 | 181 | (9.92) | ε3 | 0.847 | ||
ε3ε3 | 1312 | (71.89) | ε4 | 0.096 | ||||
ε3ε4 | 287 | (15.73) | ||||||
ε4ε4 | 22 | (1.21) | ||||||
ε2ε4 | 19 | (1.04) | ||||||