Skip to main content

Table 5 TNF-α haplotypes and disease progression in HIV-1-infected patients.

From: Effect of TNF-α genetic variants and CCR5Δ32 on the vulnerability to HIV-1 infection and disease progression in Caucasian Spaniards

Haplotypes

TNF-αSNP

n (estimated frequencies in %)

OR

OR 95CI%

pvalue *

 

-238 G>A

-308 G>A

-863 G>A

Total

(n = 184)

HIV-1 TP

(n = 109)

HIV-1 LTNP

(n = 75)

   

H1

G

G

C

131 (70.73%)

80 (73.44%)

51 (66.70%)

1.00

  

H2

G

G

A

23 (12.51%)

12 (9.90%)

11 (16.04%)

1.83

0.92 - 3.64

0.09

H3

G

A

C

19 (10.45%)

12 (9.83%)

7 (9.95%)

1.20

0.60 - 2.41

0.61

H4

A

G

C

11 (5.99%)

5 (4.25%)

6 (7.30%)

1.84

0.68 - 4.95

0.23

rare

*

*

*

0 (0.32%)

-

-

1.00

-

1.00

  1. * p value for comparisons of each haplotype with a frequency greater than 1% with the most common haplotype (H1)
  2. HIV-1 TP: HIV-1-infected typical progressors
  3. HIV-1 LTNP: HIV-1-infected long-term non-progressors