SNP | Risk allele | Risk allele frequency | Study population (no. cases) | OR§ (95% CI) | P-value | Genetic approach | Ref.* |
---|---|---|---|---|---|---|---|
rs2891168 | G | 0.59 | Europeans (4251) | 1.29 (1.20-1.38) | 6 × 10-13 | Case-control study | [15] |
rs10811661 | T | 0.85 | Finns (2314) | 1.20 (1.07-1.36) | 2.2 × 10-3 | GWAS | [11] |
 |  | 0.82 | UK (5681) | 1.19 (1.11-1.28) | 4.9 × 10-7 | Meta-analysis of GWAS | [12] |
 |  | 0.83 | Scandinavians Poles, US (6529) | 1.20 (1.12-1.28) | 5.4 × 10-8 | GWAS | [13] |
 |  | 0.86 | Dutch (9132) | 1.30 (1.16-1.47) | 1 × 10-5 | Validation of GWAS | [24] |
 |  | 0.56 | Chinese Hans (1302) | 1.31 (1.12-1.54) | 1 × 10-3 | Replication study | [25] |