Table 5 Adjusted geometric means (95% confidence intervals) of serum homocysteine (umol/L)*
From: Gene polymorphisms in association with emerging cardiovascular risk markers in adult women
Genotype | Minimally adjusted model LSmean (95% CI) | Punadjusted | PFDR-adjusted | Fully adjusted model LSmean (95% CI) | Punadjusted | PFDR-adjusted |
|---|---|---|---|---|---|---|
rs1801133 (MTHFR) | Â | 0.0002 | 0.0054 | Â | 0.0002 | 0.0052 |
TT | 9.9 (8.9-11.1) | Â | Â | 9.8 (8.9-10.8) | Â | Â |
TC | 8.2 (8.0-8.5) | Â | Â | 8.2 (7.9-8.5) | Â | Â |
CC | 7.7 (7.5-8.0) | Â | Â | 7.7 (7.6-7.9) | Â | Â |
rs2066470 (MTHFR) | Â | 0.05 | 0.46 | Â | 0.022 | 0.28 |
TT | 8.2(7.4-9.1) | Â | Â | 8.1 (7.1-9.3) | Â | Â |
TC | 7.8 (7.5-8.1) | Â | Â | 7.7 (7.5-8.0) | Â | Â |
CC | 8.2 (8.0-8.4) | Â | Â | 8.2 (8.0-8.4) | Â | Â |
rs1801131 (MTHFR) | Â | 0.02 | 0.28 | Â | 0.05 | 0.28 |
CC | 7.9 (7.4-8.4) | Â | Â | 8.0 (7.3-8.8) | Â | Â |
CA | 7.8 (7.6-8.1) | Â | Â | 7.8 (7.5-8.1) | Â | Â |
AA | 8.5 (8.1-8.8) | Â | Â | 8.4 (8.1-8.7) | Â | Â |
rs1799963 (F2) | Â | 0.16 | 0.85 | Â | 0.039 | 0.28 |
AA | -a | - | Â | - | Â | Â |
AG | 7.7 (7.1-8.4) | Â | Â | 7.5 (6.9-8.2) | Â | Â |
GG | 8.2 (8.0-8.4) | Â | Â | 8.2 (7.9-8.3) | Â | Â |
rs1042713 (ADRB2) | Â | 0.17 | 0.85 | Â | 0.04 | 0.28 |
AA | 8.1 (7.7-8.6) | Â | Â | 8.1 (7.7-8.5) | Â | Â |
AG | 8.4 (8.1-8.7) | Â | Â | 8.4 (8.1-8.7) | Â | Â |
GG | 7.9 (7.6-8.2) | Â | Â | 7.8 (7.5-8.2) | Â | Â |