| n | Genotype, n (%) | MAF, % | OR (95% CI) | P | HWE |
---|
| | 11 | 12 | 22 | | | | |
---|
rs6548238
| |
CC
|
CT
|
TT
| | | | |
Normal weight | 523 | 356 (68) | 148 (28) | 19 (4) | 18 | | | 0.461 |
Obese | 500 | 378 (76) | 115 (23) | 7 (1) | 13 | 1.450 (1.137-1.850) | 0.002 | 0.586 |
rs7561317
| |
GG
|
GA
|
AA
| | | | |
Normal weight | 523 | 348 (67) | 156 (30) | 19 (4) | 19 | | 0.001 | 0.770 |
Obese | 499 | 375 (75) | 117 (23) | 7 (1) | 13 | 1.507 (1.184-1.918) | | 0.530 |
- Data are number of subjects in each group and number of subjects for each genotype (% in each group). Minor allele frequency (MAF) for each group is given as percentage. Odds ratio (OR) with a 95% confidence interval (CI) was calculated assuming an additive model. Association with obesity was determined comparing subjects with normal weight and with obesity. P indicates p-values adjusted for sex. HWE indicates p-values for deviation from Hardy-Weinberg Equilibrium.