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Figure 2 | BMC Medical Genetics

Figure 2

From: The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

Figure 2

Multiple sequence alignment of the TMEM18 family. The protein sequences were aligned using mafft-einsi with the default parameters and viewed and edited with Jalview. The column color intensity corresponds to the degree of conservation and completely conserved residues are marked with a red star. The predicted transmembrane helices of the human TMEM18 protein are represented by pink boxes and the predicted nuclear localization signals for the mouse and human are marked with red boxes in the sequence.

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