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Table 1 Clinical characteristics of the study population

From: Association analysis of ADPRT1, AKR1B1, RAGE, GFPT2 and PAI-1 gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes

Characteristics

DMa

(N = 225)

CRIb

(N = 196)

P

Gender (M/F)

76/149

65/131

0.89d

Age (years)

60.6 ± 11.5

57 ± 12.8

0.10c

Duration of Diabetes (years)

17.07 ± 6.69

10.4 ± 7.7

<0.05c

Hb A1c (%)

7.3 ± 1.0

7.5 ± 1.1

0.949c

Systolic pressure (mm Hg) *

140 (106-190)

150 (110-210)

0.002e

Diastolic pressure (mm Hg) *

84 (80-104)

90 (70-110)

0.025e

Serum creatinine (μmol/l) *

84 (35-108)

177 (124-1112)

<<0.05e

fUAER (mg/l) *

10 (1-16)

864 (320-1584)

<<0.05e

gGFR (mls/min/1.73 m2)

81.44 ± 21.85

27.83 ± 24

<<0.05c

Serum triglyceride (mmol/l)

1.7 ± 0.67

1.8 ± 1.4

0.307c

Serum cholesterol (mmol/l)

4.8 ± 0.97

4.9 ± 0.92

0.852c

Retinopathy (%)

24

88

 

Non proliferative (%)

15

35

 

Proliferative (%)

8.6

53

<<0.05d

Cardiovascular events (%)

3

8.3

 
  1. Data presented as mean ± SD (* median and range). atype 2 diabetes subjects without nephropathy (DM); bwith diabetic renal insufficiency (CRI); cStudent's t test; dPearson's χ2 test; eMann-Whitney U test, fUrinary albumin excretion rate, gGlomerular filtration rate.