Skip to main content

Table 1 Clinical characteristics of the study population

From: Association analysis of ADPRT1, AKR1B1, RAGE, GFPT2 and PAI-1 gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes

Characteristics DMa
(N = 225)
CRIb
(N = 196)
P
Gender (M/F) 76/149 65/131 0.89d
Age (years) 60.6 ± 11.5 57 ± 12.8 0.10c
Duration of Diabetes (years) 17.07 ± 6.69 10.4 ± 7.7 <0.05c
Hb A1c (%) 7.3 ± 1.0 7.5 ± 1.1 0.949c
Systolic pressure (mm Hg) * 140 (106-190) 150 (110-210) 0.002e
Diastolic pressure (mm Hg) * 84 (80-104) 90 (70-110) 0.025e
Serum creatinine (μmol/l) * 84 (35-108) 177 (124-1112) <<0.05e
fUAER (mg/l) * 10 (1-16) 864 (320-1584) <<0.05e
gGFR (mls/min/1.73 m2) 81.44 ± 21.85 27.83 ± 24 <<0.05c
Serum triglyceride (mmol/l) 1.7 ± 0.67 1.8 ± 1.4 0.307c
Serum cholesterol (mmol/l) 4.8 ± 0.97 4.9 ± 0.92 0.852c
Retinopathy (%) 24 88  
Non proliferative (%) 15 35  
Proliferative (%) 8.6 53 <<0.05d
Cardiovascular events (%) 3 8.3  
  1. Data presented as mean ± SD (* median and range). atype 2 diabetes subjects without nephropathy (DM); bwith diabetic renal insufficiency (CRI); cStudent's t test; dPearson's χ2 test; eMann-Whitney U test, fUrinary albumin excretion rate, gGlomerular filtration rate.