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Table 3 IL1R1 haplotype frequencies in hand OA patients and in controls and the p-value for the difference (one allele versus all other alleles combined) based on the Haploview program [30].

From: Allelic variants of IL1R1gene associate with severe hand osteoarthritis

   Allele frequenciesa
No. Allele Controls Hand OAa p-value
1 TGGGA 0.381 0.440 0.147
2 TGGGG 0.218 0.212 0.865
3 CAAAG 0.188 0.104 0.008
4 TGAGG 0.115 0.123 0.772
5 TAAAG 0.053 0.048 0.796
6 others - -  
  1. a Only the index case of each hand OA family was included
  2. Only haplotypes with frequency of over 0.05 in control sample are shown. The SNPs used to estimate the haplotypes were rs1465325, rs956730, rs3917225, rs2287047 and rs3771200, respectively.