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Table 1 The number of cases and controls according to case definition and sample provenance.

From: Allelic variants of IL1R1gene associate with severe hand osteoarthritis

 

Number of subjects

 

Total

Male

Female

Hand OA material

168a

36

132

44 families with ≥ 2 DIP OA casesb

116

22

94

4 families with 1 DIP OA caseb

15

5

10

Additional radiologically verified DIP OA casesb

9

4

5

Physician diagnosed hand OA casesc

28

5

23

Knee OA materialb

113

27

86

Controls

436

277

159

Total

689

335

354

  1. a = The total number of affected individuals was 134 of which 85 were unrelated
  2. b = Radiologically verified OA cases
  3. c = Physician diagnosed hand OA; this group is also a part of radiological knee OA material