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Table 3 Adjusted odds ratio (AOR) and 95% confidence intervals (CIs) of hepatocellular carcinoma associated with genotypic frequencies in different gender groups.

From: Glutathione S-Transferase P1 (GSTP1) gene polymorphism increases age-related susceptibility to hepatocellular carcinoma

Variable Controls n (%) Patients n (%) OR (95% CI) p value AOR (95% CI) p value
  Male
GSTP1 n = 257 n = 128   
II 179 (69.7%) 76 (59.4%) 1.00 1.00
IV 72 (28.0%) 47 (36.7%) 1.53 (0.9-2.4) p = 0.06 1.41 (0.8-2.2) p = 0.14
VV 6 (2.3%) 5 (3.9%) 1.96 (0.5-6.6) p = 0.27 1.95 (0.5-6.7) p = 0.29
GSTA1 n = 257 n = 128   
AA 200 (77.8%) 107 (83.6%) 1.00 1.00
AB 53 (20.6%) 20 (15.6%) 0.70 (0.4-1.2) p = 0.22 0.76 (0.4-1.3) p = 0.35
BB 4 (1.6%) 1 (0.8%) 0.46 (0.05-4.2) p = 0.49 0.45 (0.04-4.2) p = 0.49
  Female
GSTP1 n = 129 n = 49   
II 93 (72.1%) 36 (73.5%) 1.00 1.00
IV 35 (27.1%) 11 (22.4%) 0.81 (0.3-1.7) p = 0.60 0.57 (0.2-1.5) p = 0.28
VV 1 (0.8%) 2 (4.1%) 5.16 (0.4-58.7) p = 0.18 3.67 (0.1-107.8) p = 0.45
GSTA1 n = 129 n = 49   
AA 104 (80.6%) 39 (79.6%) 1.00 1.00
AB 25 (19.4%) 10 (20.4%) 1.06 (0.4-2.4) p = 0.87 1.70 (0.5-5.3) p = 0.36
BB 0 (0%) 0 (0%) - -
  1. The odds ratios (ORs) with their 95% CIs were estimated by logistic regression models.
  2. The adjusted odds ratios (AORs) with their 95% CIs were estimated by multiple logistic regression models, after controlling for age and genotypes for each estimated variable.