Table 3 Adjusted odds ratio (AOR) and 95% confidence intervals (CIs) of hepatocellular carcinoma associated with genotypic frequencies in different gender groups.
Variable | Controls n (%) | Patients n (%) | OR (95% CI) p value | AOR (95% CI) p value |
|---|---|---|---|---|
| Â | Male | |||
GSTP1 | n = 257 | n = 128 | Â | Â |
II | 179 (69.7%) | 76 (59.4%) | 1.00 | 1.00 |
IV | 72 (28.0%) | 47 (36.7%) | 1.53 (0.9-2.4) p = 0.06 | 1.41 (0.8-2.2) p = 0.14 |
VV | 6 (2.3%) | 5 (3.9%) | 1.96 (0.5-6.6) p = 0.27 | 1.95 (0.5-6.7) p = 0.29 |
GSTA1 | n = 257 | n = 128 | Â | Â |
AA | 200 (77.8%) | 107 (83.6%) | 1.00 | 1.00 |
AB | 53 (20.6%) | 20 (15.6%) | 0.70 (0.4-1.2) p = 0.22 | 0.76 (0.4-1.3) p = 0.35 |
BB | 4 (1.6%) | 1 (0.8%) | 0.46 (0.05-4.2) p = 0.49 | 0.45 (0.04-4.2) p = 0.49 |
| Â | Female | |||
GSTP1 | n = 129 | n = 49 | Â | Â |
II | 93 (72.1%) | 36 (73.5%) | 1.00 | 1.00 |
IV | 35 (27.1%) | 11 (22.4%) | 0.81 (0.3-1.7) p = 0.60 | 0.57 (0.2-1.5) p = 0.28 |
VV | 1 (0.8%) | 2 (4.1%) | 5.16 (0.4-58.7) p = 0.18 | 3.67 (0.1-107.8) p = 0.45 |
GSTA1 | n = 129 | n = 49 | Â | Â |
AA | 104 (80.6%) | 39 (79.6%) | 1.00 | 1.00 |
AB | 25 (19.4%) | 10 (20.4%) | 1.06 (0.4-2.4) p = 0.87 | 1.70 (0.5-5.3) p = 0.36 |
BB | 0 (0%) | 0 (0%) | - | - |