|
Variable
|
Controls n (%)
|
Patients n (%)
|
OR (95% CI) p value
|
AOR (95% CI) p value
|
|---|
| |
Male
|
|---|
|
GSTP1
|
n = 257
|
n = 128
| | |
|
II
|
179 (69.7%)
|
76 (59.4%)
|
1.00
|
1.00
|
|
IV
|
72 (28.0%)
|
47 (36.7%)
|
1.53 (0.9-2.4) p = 0.06
|
1.41 (0.8-2.2) p = 0.14
|
|
VV
|
6 (2.3%)
|
5 (3.9%)
|
1.96 (0.5-6.6) p = 0.27
|
1.95 (0.5-6.7) p = 0.29
|
|
GSTA1
|
n = 257
|
n = 128
| | |
|
AA
|
200 (77.8%)
|
107 (83.6%)
|
1.00
|
1.00
|
|
AB
|
53 (20.6%)
|
20 (15.6%)
|
0.70 (0.4-1.2) p = 0.22
|
0.76 (0.4-1.3) p = 0.35
|
|
BB
|
4 (1.6%)
|
1 (0.8%)
|
0.46 (0.05-4.2) p = 0.49
|
0.45 (0.04-4.2) p = 0.49
|
| |
Female
|
|
GSTP1
|
n = 129
|
n = 49
| | |
|
II
|
93 (72.1%)
|
36 (73.5%)
|
1.00
|
1.00
|
|
IV
|
35 (27.1%)
|
11 (22.4%)
|
0.81 (0.3-1.7) p = 0.60
|
0.57 (0.2-1.5) p = 0.28
|
|
VV
|
1 (0.8%)
|
2 (4.1%)
|
5.16 (0.4-58.7) p = 0.18
|
3.67 (0.1-107.8) p = 0.45
|
|
GSTA1
|
n = 129
|
n = 49
| | |
|
AA
|
104 (80.6%)
|
39 (79.6%)
|
1.00
|
1.00
|
|
AB
|
25 (19.4%)
|
10 (20.4%)
|
1.06 (0.4-2.4) p = 0.87
|
1.70 (0.5-5.3) p = 0.36
|
|
BB
|
0 (0%)
|
0 (0%)
|
-
|
-
|
- The odds ratios (ORs) with their 95% CIs were estimated by logistic regression models.
- The adjusted odds ratios (AORs) with their 95% CIs were estimated by multiple logistic regression models, after controlling for age and genotypes for each estimated variable.
