Variable

Controls n (%)

Patients n (%)

OR (95% CI) p value

AOR (95% CI) p value



Age > 57 years old


GSTP1

n = 149

n = 129
  
II

93 (62.4%)

85 (65.9%)

1.00

1.00

IV

52 (34.9%)

40 (31.0%)

0.84 (0.51.3) p = 0.50

0.88 (0.51.4) p = 0.63

VV

4 (2.7%)

4 (3.1%)

1.09 (0.24.5) p = 0.90

1.06 (0.24.6) p = 0.93

GSTA1

n = 149

n = 129
  
AA

122 (81.9%)

106 (82.2%)

1.00

1.00

AB

24 (16.1%)

22 (17.1%)

1.05 (0.51.9) p = 0.86

1.05 (0.52.0) p = 0.87

BB

3 (2.0%)

1 (0.8%)

0.38 (0.033.7) p = 0.40

0.47 (0.044.68) p = 0.52


Age ≤ 57 years old

GSTP1

n = 237

n = 48
  
II

179 (75.5%)

27 (56.3%)

1.00

1.00

IV

55 (23.2%)

18 (37.5%)

2.17 (1.14.2) p = 0.02

2.18 (1.14.3) p = 0.02

VV

3 (1.3%)

3 (6.2%)

6.63 (1.234.5) p = 0.02

5.64 (1.131.8) p = 0.04

GSTA1

n = 237

n = 48
  
AA

182 (76.8%)

40 (83.3%)

1.00

1.00

AB

54 (22.8%)

8 (16.7%)

0.67 (0.21.5) p = 0.34

0.62 (0.21.4) p = 0.28

BB

1 (0.4%)

0 (0%)

 p = 0.99

 p = 0.99

 The odds ratios (ORs) with their 95% CIs were estimated by logistic regression models.
 The adjusted odds ratios (AORs) with their 95% CIs were estimated by multiple logistic regression models, after controlling for gender and genotypes for each estimated variable.