Table 2 Adjusted odds ratio (AOR) and 95% confidence intervals (CIs) of hepatocellular carcinoma associated with genotypic frequencies in different age groups.
Variable | Controls n (%) | Patients n (%) | OR (95% CI) p value | AOR (95% CI) p value |
|---|---|---|---|---|
| Â | Age > 57 years old | |||
GSTP1 | n = 149 | n = 129 | Â | Â |
II | 93 (62.4%) | 85 (65.9%) | 1.00 | 1.00 |
IV | 52 (34.9%) | 40 (31.0%) | 0.84 (0.5-1.3) p = 0.50 | 0.88 (0.5-1.4) p = 0.63 |
VV | 4 (2.7%) | 4 (3.1%) | 1.09 (0.2-4.5) p = 0.90 | 1.06 (0.2-4.6) p = 0.93 |
GSTA1 | n = 149 | n = 129 | Â | Â |
AA | 122 (81.9%) | 106 (82.2%) | 1.00 | 1.00 |
AB | 24 (16.1%) | 22 (17.1%) | 1.05 (0.5-1.9) p = 0.86 | 1.05 (0.5-2.0) p = 0.87 |
BB | 3 (2.0%) | 1 (0.8%) | 0.38 (0.03-3.7) p = 0.40 | 0.47 (0.04-4.68) p = 0.52 |
|  | Age ≤ 57 years old | |||
GSTP1 | n = 237 | n = 48 | Â | Â |
II | 179 (75.5%) | 27 (56.3%) | 1.00 | 1.00 |
IV | 55 (23.2%) | 18 (37.5%) | 2.17 (1.1-4.2) p = 0.02 | 2.18 (1.1-4.3) p = 0.02 |
VV | 3 (1.3%) | 3 (6.2%) | 6.63 (1.2-34.5) p = 0.02 | 5.64 (1.1-31.8) p = 0.04 |
GSTA1 | n = 237 | n = 48 | Â | Â |
AA | 182 (76.8%) | 40 (83.3%) | 1.00 | 1.00 |
AB | 54 (22.8%) | 8 (16.7%) | 0.67 (0.2-1.5) p = 0.34 | 0.62 (0.2-1.4) p = 0.28 |
BB | 1 (0.4%) | 0 (0%) | - p = 0.99 | - p = 0.99 |