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Table 2 Genotype and allele frequencies for the LCE3C_LCE3B-del (parentheses indicate frequencies).

From: Mutation analysis of the LCE3B/LCE3C genes in Psoriasis

 

LCE3 genotypes

Alleles

 

II

ID

DD

D

I

Controls

(n = 400)

60

(15)

196

(51)

144

(36)

493

(0.61)

307

(0.39)

Total patients

(n = 405)

52

(13)

204

(50)

149

(37)

502

(0.62)

308

(0.38)

Psor. Vulgaris

(n = 324)

30

(9)

157

(49)

137

(42)

431

(0.67)

217

(0.33)

Familial Ps

(n = 221)

32

(14)

113

(51)

76

(34)

265

(0.60)

177

(0.40)

Sporadic Ps

(n = 184)

20

(11)

91

(50)

73

(39)

237

(0.64)

131

(036)

Early onset Ps

(n = 243)

32

(13)

124

(51)

87

(36)

298

(0.61)

188

(0.39)

Late onset Ps

(n = 162)

20

(12)

77

(48)

65

(40)

207

(0.64)

117

(0.36)

Non Severe Ps

(n = 243)

28

(11)

126

(52)

89

(37)

304

(0.63)

182

(0.37)

Severe Ps

(n = 162)

24

(15)

78

(48)

60

(37)

198

(0.61)

126

(0.39)

Arthritis

(n = 83)

8

(10)

49

(59)

26

(31)

101

(0.61)

65

(0.39)

Non arthritis

(n = 322)

44

(14)

155

(45)

123

(41)

401

(0.62)

243

(0.38)

Cw6 positive

(n = 158)

11

(8)

81

(51)

66

(42)

213

(0.67)

103

(0.33)

Cw6 negative

(n = 247)

40

(16)

123

(50)

84

(34)

291

(0.59)

203

(0.41)

Psor. Vulgaris

Non arhritis

(n = 274)

25

(9)

128

(47)

121

(44)

370

(0.68)

178

(0.32)