Skip to main content

Table 4 SNPs with the highest evidence of association in the region including the GABRR2 and the UBE2J1 genes (chromosome 6)#.

From: A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2with serum creatinine level

Study GENE name Position Genotype (Ref. All.) Ref. All. Freq. N Beta* SE p value**
EUROSPAN GABRR2 rs6942204 90072687 C/T (C) 0.34 4001 0.0497 0.0213 0.0196
EUROSPAN GABRR2 rs3777514 90077300 A/C (A) 0.20 3998 0.0855 0.0244 4.5 × 10-4
EUROSPAN Intergenic rs2064831 90089661 C/T (C) 0.18 3995 0.1018 0.0257 7.2 × 10-5
EUROSPAN Intergenic rs12195070 90090455 C/T (T) 0.19 3998 0.0722 0.0254 4.5 × 10-3
EUROSPAN UBE2J1 rs1998576 90099856 A/G (A) 0.18 3997 0.0993 0.0253 8.6 × 10-5
EUROSPAN UBE2J1 rs12189673 90103123 C/T (C) 0.30 3980 -0.0653 0.0213 2.2 × 10-3
EUROSPAN UBE2J1 rs1065657 90103732 C/T (T) 0.45 3999 0.0499 0.0197 0.0115
EUROSPAN UBE2J1 rs7760851 90109323 A/G (G) 0.49 3980 -0.0505 0.0196 0.0100
EUROSPAN UBE2J1 rs1062108 90132078 C/T (T) 0.42 3996 -0.0435 0.0198 0.0280
POPGEN GABRR2 rs9362633 90058261 A/G (G) 0.05 1136 -0.2430 0.0795 2.2 × 10-3
POPGEN GABRR2 rs7764923 90079640 C/T (T) 0.23 1140 -0.1144 0.0387 3.1 × 10-3
POPGEN GABRR2 rs2236204 90081831 G/T (T) 0.17 1121 -0.1190 0.0436 6.4 × 10-3
POPGEN Intergenic rs10944443 90087709 C/G (C) 0.15 1113 -0.1203 0.0469 0.0103
POPGEN Intergenic rs12195070 90090455 C/T (T) 0.18 1140 -0.1155 0.0430 7.2 × 10-3
POPGEN Intergenic rs12195078 90090511 C/T (T) 0.15 1128 -0.1261 0.0460 6.1 × 10-3
POPGEN UBE2J1 rs9048 90094300 C/T (T) 0.18 1139 -0.1230 0.0417 3.1 × 10-3
POPGEN UBE2J1 rs9351207 90115388 C/T (T) 0.24 1131 -0.0791 0.0387 0.0412
  1. # association models were adjusted for age and sex; *in standard deviations; **p value: for EUROSPAN, the p value refers to the meta-analysis of the five individual GWA studies, for popgen, the p value is from the linear regression analysis (for details, see Methods).
Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us