Table 4 SNPs with the highest evidence of association in the region including the GABRR2 and the UBE2J1 genes (chromosome 6)#.
Study | GENE | name | Position | Genotype (Ref. All.) | Ref. All. Freq. | N | Beta* | SE | p value** |
|---|---|---|---|---|---|---|---|---|---|
EUROSPAN | GABRR2 | rs6942204 | 90072687 | C/T (C) | 0.34 | 4001 | 0.0497 | 0.0213 | 0.0196 |
EUROSPAN | GABRR2 | rs3777514 | 90077300 | A/C (A) | 0.20 | 3998 | 0.0855 | 0.0244 | 4.5 × 10-4 |
EUROSPAN | Intergenic | rs2064831 | 90089661 | C/T (C) | 0.18 | 3995 | 0.1018 | 0.0257 | 7.2 × 10-5 |
EUROSPAN | Intergenic | rs12195070 | 90090455 | C/T (T) | 0.19 | 3998 | 0.0722 | 0.0254 | 4.5 × 10-3 |
EUROSPAN | UBE2J1 | rs1998576 | 90099856 | A/G (A) | 0.18 | 3997 | 0.0993 | 0.0253 | 8.6 × 10-5 |
EUROSPAN | UBE2J1 | rs12189673 | 90103123 | C/T (C) | 0.30 | 3980 | -0.0653 | 0.0213 | 2.2 × 10-3 |
EUROSPAN | UBE2J1 | rs1065657 | 90103732 | C/T (T) | 0.45 | 3999 | 0.0499 | 0.0197 | 0.0115 |
EUROSPAN | UBE2J1 | rs7760851 | 90109323 | A/G (G) | 0.49 | 3980 | -0.0505 | 0.0196 | 0.0100 |
EUROSPAN | UBE2J1 | rs1062108 | 90132078 | C/T (T) | 0.42 | 3996 | -0.0435 | 0.0198 | 0.0280 |
POPGEN | GABRR2 | rs9362633 | 90058261 | A/G (G) | 0.05 | 1136 | -0.2430 | 0.0795 | 2.2 × 10-3 |
POPGEN | GABRR2 | rs7764923 | 90079640 | C/T (T) | 0.23 | 1140 | -0.1144 | 0.0387 | 3.1 × 10-3 |
POPGEN | GABRR2 | rs2236204 | 90081831 | G/T (T) | 0.17 | 1121 | -0.1190 | 0.0436 | 6.4 × 10-3 |
POPGEN | Intergenic | rs10944443 | 90087709 | C/G (C) | 0.15 | 1113 | -0.1203 | 0.0469 | 0.0103 |
POPGEN | Intergenic | rs12195070 | 90090455 | C/T (T) | 0.18 | 1140 | -0.1155 | 0.0430 | 7.2 × 10-3 |
POPGEN | Intergenic | rs12195078 | 90090511 | C/T (T) | 0.15 | 1128 | -0.1261 | 0.0460 | 6.1 × 10-3 |
POPGEN | UBE2J1 | rs9048 | 90094300 | C/T (T) | 0.18 | 1139 | -0.1230 | 0.0417 | 3.1 × 10-3 |
POPGEN | UBE2J1 | rs9351207 | 90115388 | C/T (T) | 0.24 | 1131 | -0.0791 | 0.0387 | 0.0412 |