Skip to main content

Advertisement

Table 3 SNPs with the highest evidence of association in the region upstream the SYT1 gene.#

From: A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2with serum creatinine level

Study name position Genotype (Ref. All.) Ref. All. Freq. n Beta* SE p value**
EUROSPAN rs11838060 77997790 G/T (T) 0.14 3163 -0.0696 0.0312 0.0258
EUROSPAN rs10506807 78005428 C/T (C) 0.13 4000 -0.1141 0.0287 7.0 × 10-5
EUROSPAN rs12300068 78005502 A/G (A) 0.13 3997 -0.1158 0.0288 5.7 × 10-5
EUROSPAN rs7972593 78013149 C/T (T) 0.12 3989 -0.0978 0.0300 1.1 × 10-3
EUROSPAN rs11112829 78029267 C/T (C) 0.13 4000 -0.1135 0.0287 7.5 × 10-5
POPGEN rs12312807 77957336 A/G (A) 0.11 1139 0.1480 0.0539 6.1 × 10-3
POPGEN rs1527119 77964145 G/T (G) 0.11 1139 0.1471 0.0539 6.4 × 10-3
POPGEN rs1033196 77966968 C/T (T) 0.14 1128 0.1320 0.0479 5.8 × 10-3
POPGEN rs2950383 77973538 A/G (A) 0.37 1103 -0.1553 0.0359 2.0 × 10-5
POPGEN rs1356022 77974533 C/T (C) 0.14 1140 0.1300 0.0475 6.2 × 10-3
POPGEN rs12317960 77977824 C/T (T) 0.14 1140 0.1249 0.0474 8.5 × 10-3
POPGEN rs10506806 77979113 C/T (T) 0.31 1120 0.1012 0.0362 5.1 × 10-3
POPGEN rs11610381 77979918 C/T (C) 0.14 1134 0.1321 0.0476 5.5 × 10-3
POPGEN rs7971081 77980051 C/T (C) 0.14 1140 0.1296 0.0474 6.3 × 10-3
  1. # association models were adjusted for age and sex; *in standard deviations; **p value: for EUROSPAN, the p value refers to the meta-analysis of the five individual GWA studies, for popgen, the p value is from the linear regression analysis (for details, see Methods).