Skip to main content

Advertisement

Table 1 Characteristics of studies and study participants.

From: A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2with serum creatinine level

  EUROSPAN REPLICATION STUDIES
Study name ERF MICROS NSPHS ORCADES VIS popgen Korcula
Nationality The Netherlands Italy Sweden UK Croatia Germany Croatia
Population type isolated isolated isolated isolated isolated general isolated
Genotyping platform Illumina 318 K Illumina 318 K Illumina 318 K Illumina 318 K Illumina 318 K Affymetrix 1000 K Illumina 370 K
Sample size* 775 1086 653 718 774 1140 895
Females: n (%) 472 (61%) 615 (57%) 345 (53%) 385 (54%) 454 (59%) 534 (47%) 572 (64%)
Age: mean (sd) 53 (15) 45 (16) 47 (21) 54 (16) 57 (15) 54 (15) 56 (14)
Diabetes: n (%) 36 (4.9%) 39 (3.6%) 44 (6.7%) 21 (3.0%) 72 (9.4%) 18 (1.6%) 93 (10.3%)
AHT # : n (%) 190 (24.5%) 85 (7.8%) 124 (19.0%) 152 (21.2%) 192 (25.2%) Not available 197 (22.0%)
S CR mg/dl: mean (sd)        
Males 1.01 (0.20) 0.96 (0.14) 0.94 (0.20) 0.97 (0.15) 1.01 (0.31) 0.93 (0.15) 0.92 (0.15)
Females 0.85 (0.21) 0.78 (0.12) 0.75 (0.14) 0.77 (0.19) 0.79 (0.27) 0.74 (0.12) 0.75 (0.12)
eGFR ml/min/1.73 m2        
Males 81.1 (19.0) 87.8 (15.1) 92.2 (22.1) 84.3 (16.0) 82.0 (19.4) 88.0 (17.5) 77.1 (14.9)
Females 75.8 (20.5) 83.4 (16.8) 88.7 (19.2) 81.5 (18.5) 81.0 (19.8) 85.5 (17.2) 72.4 (14.1)
  1. * Number of individuals with available creatinine, sex, and age information.
  2. # AHT: Anti-hypertensive treatment
  3. Estimated using the updated abbreviated MDRD study equation [58]