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Figure 6 | BMC Medical Genetics

Figure 6

From: A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2with serum creatinine level

Figure 6

Genomic structure and association results at the GABRR2-UBE2J1 locus. Upper panel: -log10(p values) are plotted by physical position for the EUROSPAN discovery meta-analysis (red squares), the popgen (blue squares) and the Korcula (green squares) replication cohorts. Middle panel: linkage disequilibrium (LD) as quantified by r2 (the higher the LD, the darker the color, with black indicating perfect LD), based upon the HapMap-CEU database, Phase III/Release 2, (NCBI build 36). Lower panel: genes located in the plotted region, with coding exons indicated by black rectangles and orientation.

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