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Figure 2 | BMC Medical Genetics

Figure 2

From: A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2with serum creatinine level

Figure 2

Manhattan plot of -log 10 (p values) from the meta-analysis of five GWA studies. GWA results were combined across all studies by fixed-effects meta-analysis using inverse variance weighting. Square dots indicate SNPs satisfying criteria for selection of candidate regions. SNPs within replicated regions are colored in dark red and SNPs within non-replicated regions in pink. The genomic control factor of λ = 1.004, assessed by the quantile-quantile plot in the upper-right panel, indicates that cryptic relatedness and population structure have been modeled appropriately.

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