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Table 3 Haplotype frequency distribution of the MMP-2 and -9 genes, and association with stroke outcome.

From: Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloproteinase-9 genes significantly influence functional outcome after stroke

   Whole sample Ischemic subset
Gene Haplotype Haplotype frequency Good recovery (%) Poor recovery (%) χ2 P Haplotype frequency Good recovery (%) Poor recovery (%) χ2 P
MMP-2 rs11643630-rs243866-rs243865 0.200 17.2 22.7 5.150 0.0233 0.198 16.8 23.5 6.125 0.0133
  TAT           
MMP-2 rs1477017-rs17301608-rs1132896-rs1053605-rs2241145-rs243849-rs243842-rs183112 0.011 1.8 0.4 4.776 0.0289 0.014 2.1 0.6 3.372 0.0663
  ACGCGTTG           
MMP-9 rs8113877-rs3918253-rs2236416 0.034 4.8 1.9 7.403 0.0065 0.038 4.9 2.4 3.680 0.0551
  TCA           
  1. Only haplotypes with significant association results are presented.
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BMC Medical Genetics

ISSN: 1471-2350

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