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Table 2 Fetal and infant characteristics (n = 2,414)

From: Glucocorticoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study

 

Boys

(n = 1,233)

Girls

(n = 1,181)

P-value

Second trimester

   

Gestational age (weeks)

20.6 (18.7 - 23.3)

20.4 (18.5 - 23.1)

<0.01

Estimated fetal weight (grams)

386 (91)

374 (86)

<0.01

Femur length (mm)

33.3 (3.2)

33.2 (3.3)

0.55

Head circumference (mm)

181.0 (13.1)

177.2 (13.0)

<0.01

Third trimester

   

Gestational age (weeks)

30.4 (28.6 - 33.0)

30.3 (28.3 - 32.8)

<0.01

Estimated fetal weight (grams)

1646 (258)

1620 (268)

<0.01

Femur length (mm)

57.4 (2.9)

57.4 (2.9)

0.64

Head circumference (mm)

288.8 (11.8)

283.7 (11.2)

<0.01

Birth

   

Gestational age

40.1 (35.0 - 42.4)

40.1 (35.2 - 42.1)

0.42

Weight (grams)

3518 (596)

3400 (574)

<0.01

Length (cm)*

55.1 (2.4)

54.0 (2.1)

<0.01

Head circumference)*

38.1 (1.3)

37.3 (1.2)

<0.01

Weight < 2500 grams (%)

29 (2.4)

26 (2.2)

0.80

Preterm birth (<36 weeks) (%)

41 (3.3)

37 (3.1)

0.79

Age 6 months

   

Age at visit (months)

6.2 (5.2 - 7.9)

6.2 (5.2 - 7.9)

0.28

Weight (grams)

8,078 (845)

7,540 (812)

<0.01

Length (cm)

68.5 (2.4)

66.8 (2.3)

<0.01

Head circumference (cm)

44.2 (1.3)

43.1 (1.7)

<0.01

Age 14 months

   

Age at visit (months)

14.3 (13.6 - 16.2)

14.3 (13.4 - 16.0)

0.05

Weight (grams)

10,824 (1,070)

10,191 (1,018)

<0.01

Length (cm)

78.9 (2.6)

77.5 (2.6)

<0.01

Head circumference (cm)

47.7 (1.3)

46.6 (1.1)

<0.01

Age 24 months

   

Age at visit (months)

24.8 (23.4 - 28.1)

24.8 (23.4 - 28.1)

0.48

Weight (grams)

13,140 (1,376)

12,651 (1,412)

<0.01

Length (cm)

88.9 (3.4)

87.7 (3.4)

<0.01

  1. Values are means (SDS) or medians (95% range).
  2. Differences between boys and girls were compared using independent samples t-tests.
  3. *Measured at 1 months of age