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Table 6 Odds Ratios that Could Have Been Detected Given the Sample Size and Minor Allele Frequency in the Study Population

From: Polymorphisms in IL-1β, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis

SNP

rs number

Minor Allele Frequency

Detectable Odds Ratio*

NRAMP1 INT4

rs3731865

0.12

4.19

NRAMP1 D543N

rs17235409

0.07

5.42

NRAMP1 274 C/T

rs2276631

0.19

3.56

SP 110

rs2114592

0.15

3.85

SP 110

rs3948464

0.13

4.06

IFNg +874 A/T

rs2430561

0.29

3.26

IFNg -1616G

rs2069705

0.49

3.41

IFNg +3234

rs2069718

0.43

3.27

IFNgR1 -56 C/T

rs2234711

0.45

3.31

IL-1a -889 C/T

rs1800587

0.38

3.22

IL-1B +3953 C/T

rs1143634

0.12

4.19

IL-10 -1082 G/A

rs1800896

0.35

3.21

IL-10 -592 A/C

rs1800872

0.42

3.26

MBL codon 57

rs1800451

0.15

3.85

VDR Taq1

rs731236

0.26

3.31

VDR Fok1 A/G

rs10735810

0.23

3.39

MCP-1 -2518 A/G

rs1024611

0.19

3.56

TIRAP C558T

rs7932766

0.17

3.69

P2X7 1513 A/C

rs3751143

0.12

4.19

  1. These calculations assume 80% power. This table includes SNPs that have previously been reported to be associated with tuberculosis.
  2. *Odds ratios greater than this value could have been detected in this study.