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Table 6 Odds Ratios that Could Have Been Detected Given the Sample Size and Minor Allele Frequency in the Study Population

From: Polymorphisms in IL-1β, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis

SNP rs number Minor Allele Frequency Detectable Odds Ratio*
NRAMP1 INT4 rs3731865 0.12 4.19
NRAMP1 D543N rs17235409 0.07 5.42
NRAMP1 274 C/T rs2276631 0.19 3.56
SP 110 rs2114592 0.15 3.85
SP 110 rs3948464 0.13 4.06
IFNg +874 A/T rs2430561 0.29 3.26
IFNg -1616G rs2069705 0.49 3.41
IFNg +3234 rs2069718 0.43 3.27
IFNgR1 -56 C/T rs2234711 0.45 3.31
IL-1a -889 C/T rs1800587 0.38 3.22
IL-1B +3953 C/T rs1143634 0.12 4.19
IL-10 -1082 G/A rs1800896 0.35 3.21
IL-10 -592 A/C rs1800872 0.42 3.26
MBL codon 57 rs1800451 0.15 3.85
VDR Taq1 rs731236 0.26 3.31
VDR Fok1 A/G rs10735810 0.23 3.39
MCP-1 -2518 A/G rs1024611 0.19 3.56
TIRAP C558T rs7932766 0.17 3.69
P2X7 1513 A/C rs3751143 0.12 4.19
  1. These calculations assume 80% power. This table includes SNPs that have previously been reported to be associated with tuberculosis.
  2. *Odds ratios greater than this value could have been detected in this study.