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Table 3 Of the Polymorphisms Tested that had Previously Been Reported as Associated with Tuberculosis (Table 2), the SNPs Associated with Tuberculosis in this Study

From: Polymorphisms in IL-1β, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis

Comparator groups

SNPs

P-value

Single Locus Association Tests

All patients

  

Any TB vs. PPD+

IL-1beta +3953

0.044

ExtTB vs. PPD+

IL-1beta +3953

0.049

ExtTB vs. PulmTB

none

---

Black patients

  

Any TB vs. PPD+

none

---

ExtTB vs. PPD+

none

---

ExtTB vs. PulmTB

VDR Fok1

0.018

Multifactor Dimensionality Reduction Analysis

All patients

  

Any TB vs. PPD+

TLR2 microsatellite

0.038#

ExtTB vs. PPD+

none

---

ExtTB vs. PulmTB

none

---

Black patients

  

Any TB vs. PPD+

TLR2 microsatellite

0.047*

ExtTB vs. PPD+

TLR2 microsatellite

0.002^

ExtTB vs. PulmTB

none

---

  1. SNPs with P ≤ 0.05 are listed. P-values are uncorrected.
  2. # 61% prediction accuracy
  3. * 63% prediction accuracy
  4. ^ 76% prediction accuracy