Skip to main content

Table 3 Of the Polymorphisms Tested that had Previously Been Reported as Associated with Tuberculosis (Table 2), the SNPs Associated with Tuberculosis in this Study

From: Polymorphisms in IL-1β, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis

Comparator groups SNPs P-value
Single Locus Association Tests
All patients   
Any TB vs. PPD+ IL-1beta +3953 0.044
ExtTB vs. PPD+ IL-1beta +3953 0.049
ExtTB vs. PulmTB none ---
Black patients   
Any TB vs. PPD+ none ---
ExtTB vs. PPD+ none ---
ExtTB vs. PulmTB VDR Fok1 0.018
Multifactor Dimensionality Reduction Analysis
All patients   
Any TB vs. PPD+ TLR2 microsatellite 0.038#
ExtTB vs. PPD+ none ---
ExtTB vs. PulmTB none ---
Black patients   
Any TB vs. PPD+ TLR2 microsatellite 0.047*
ExtTB vs. PPD+ TLR2 microsatellite 0.002^
ExtTB vs. PulmTB none ---
  1. SNPs with P ≤ 0.05 are listed. P-values are uncorrected.
  2. # 61% prediction accuracy
  3. * 63% prediction accuracy
  4. ^ 76% prediction accuracy