From: Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease
SNP1 | rs-ID | Genotype | Swedish material | Polish material | ||||
---|---|---|---|---|---|---|---|---|
 |  |  | Parkinson n = 1652 | Control n = 1902 | p-value3 (pc-value) | Parkinson n = 1922 | Control n = 1922 | p-value3 (pc-value) |
NFE2L2 | Â | Â | Â | Â | Â | Â | Â | Â |
   1 | rs16865105 | GG | 9 (5.5) | 18 (9.5) | 0.720 | 10 (5.5) | 9 (4.9) | 0.716 |
 |  | GT | 59 (36.0) | 62 (32.6) |  | 58 (32.0) | 65 (35.5) |  |
 |  | TT | 96 (58.5) | 110 (57.9) |  | 113 (62.5) | 109 (59.6) |  |
   2 | rs7557529 | AA | 39 (23.8) | 56 (29.5) | 0.782 | 60 (32.1) | 49 (27.4) | 0.043 |
 |  | AG | 85 (51.8) | 92 (48.4) |  | 90 (48.1) | 75 (41.9) | (0.473) |
 |  | GG | 40 (24.4) | 42 (22.1) |  | 37 (19.8) | 55 (30.7) |  |
   P1 | rs35652124 | GG | 15 (9.3) | 13 (7.1) | 0.564 | 26 (13.6) | 17 (9.1) | 0.053 |
 |  | AG | 58 (35.8) | 89 (48.3) |  | 77 (40.3) | 67 (35.8) |  |
 |  | AA | 89 (54.9) | 82 (44.6) |  | 88 (46.1) | 103 (55.1) |  |
   P2 | rs6706649 | AA | 4 (2.5) | 3 (1.6) | 1.000 | 6 (3.1) | 2 (1.1) | 1.000 |
 |  | AG | 33 (20.4) | 45 (24.5) |  | 35 (18.3) | 42 (22.5) |  |
 |  | GG | 125 (77.1) | 136 (73.9) |  | 150 (78.6) | 143 (76.4) |  |
   P3 | rs6721961 | AA | 1 (0.6) | 1 (0.5) | 0.056 | 6 (3.1) | 2 (1.1) | 0.833 |
 |  | AC | 39 (24.1) | 27 (14.7) |  | 38 (19.9) | 43 (23.0) |  |
 |  | CC | 122 (75.3) | 156 (84.8) |  | 147 (77.0) | 142 (75.9) |  |
   3 | rs2886161 | GG | 16 (9.7) | 15 (7.9) | 0.578 | 27 (14.4) | 17 (9.4) | 0.0656 |
 |  | AG | 59 (35.8) | 91 (47.9) |  | 75 (40.1) | 67 (37.0) |  |
 |  | AA | 90 (54.5) | 84 (44.2) |  | 85 (45.5) | 97 (53.6) |  |
   4 | rs1806649 | AA | 14 (8.5) | 15 (7.9) | 0.819 | 9 (4.8) | 23 (12.7) | 0.011 |
 |  | AG | 65 (39.4) | 80 (42.1) |  | 60 (32.3) | 61 (33.7) | (0.121) |
 |  | GG | 86 (52.1) | 95 (50.0) |  | 117 (62.9) | 97 (53.6) |  |
   5 | rs2001350 | GG | 1 (0.6) | 0 (0.0) | 0.016 | 4 (2.1) | 0 (0.0) | 0.663 |
 |  | AG | 35 (21.2) | 23 (12.1) | (0.224) | 28 (14.7) | 39 (20.9) |  |
 |  | AA | 129 (78.2) | 167 (87.9) |  | 158 (83.2) | 148 (79.1) |  |
   6 | rs10183914 | AA | 14 (8.5) | 25 (13.2) | 0.111 | 20 (10.8) | 28 (15.0) | 0.254 |
 |  | AG | 81 (49.1) | 89 (46.8) |  | 73 (39.2) | 73 (39.0) |  |
 |  | GG | 70 (42.4) | 76 (40.0) |  | 93 (50.0) | 86 (46.0) |  |
   7 | rs2706110 | AA | 6 (3.7) | 4 (2.1) | 0.238 | 7 (4.0) | 1 (0.6) | 0.780 |
 |  | AG | 48 (29.3) | 40 (21.1) |  | 45 (25.4) | 53 (30.6) |  |
 |  | GG | 110 (67.1) | 146 (76.8) |  | 125 (70.6) | 119 (68.8) |  |
   8 | rs13035806 | TT | 2 (1.2) | 2 (1.1) | 0.796 | 2 (1.2) | 0 (0.0) | 0.323 |
 |  | CT | 29 (17.7) | 27 (14.2) |  | 28 (16.7) | 27 (14.9) |  |
 |  | CC | 133 (81.1) | 161 (84.7) |  | 138 (82.1) | 154 (85.1) |  |
KEAP1 | Â | Â | Â | Â | Â | Â | Â | Â |
   1 | rs1048287 | CC | 1 (0.6) | 2 (1.1) | 0.589 | --- | --- | --- |
 |  | CT | 35 (21.5) | 42 (22.1) |  | --- | --- |  |
 |  | TT | 127 (77.9) | 146 (76.8) |  | --- | --- |  |
   2 | rs11085735 | TT | 2 (1.2) | 2 (1.1) | 0.737 | --- | --- | --- |
 |  | GT | 19 (11.7) | 24 (12.8) |  | --- | --- |  |
 |  | GG | 142 (87.0) | 162 (86.1) |  | --- | --- |  |
   3 | rs1048290 | GG | 22 (13.5) | 31 (16.3) | 0.372 | --- | --- | --- |
 |  | CG | 77 (47.2) | 89 (46.9) |  | --- | --- |  |
 |  | CC | 64 (39.3) | 70 (36.8) |  | --- | --- |  |