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Table 3 Single marker frequencies and associations with risk of PD

From: Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease

SNP1 rs-ID Genotype Swedish material Polish material
    Parkinson
n = 1652
Control
n = 1902
p-value3
(pc-value)
Parkinson
n = 1922
Control
n = 1922
p-value3
(pc-value)
NFE2L2         
   1 rs16865105 GG 9 (5.5) 18 (9.5) 0.720 10 (5.5) 9 (4.9) 0.716
   GT 59 (36.0) 62 (32.6)   58 (32.0) 65 (35.5)  
   TT 96 (58.5) 110 (57.9)   113 (62.5) 109 (59.6)  
   2 rs7557529 AA 39 (23.8) 56 (29.5) 0.782 60 (32.1) 49 (27.4) 0.043
   AG 85 (51.8) 92 (48.4)   90 (48.1) 75 (41.9) (0.473)
   GG 40 (24.4) 42 (22.1)   37 (19.8) 55 (30.7)  
   P1 rs35652124 GG 15 (9.3) 13 (7.1) 0.564 26 (13.6) 17 (9.1) 0.053
   AG 58 (35.8) 89 (48.3)   77 (40.3) 67 (35.8)  
   AA 89 (54.9) 82 (44.6)   88 (46.1) 103 (55.1)  
   P2 rs6706649 AA 4 (2.5) 3 (1.6) 1.000 6 (3.1) 2 (1.1) 1.000
   AG 33 (20.4) 45 (24.5)   35 (18.3) 42 (22.5)  
   GG 125 (77.1) 136 (73.9)   150 (78.6) 143 (76.4)  
   P3 rs6721961 AA 1 (0.6) 1 (0.5) 0.056 6 (3.1) 2 (1.1) 0.833
   AC 39 (24.1) 27 (14.7)   38 (19.9) 43 (23.0)  
   CC 122 (75.3) 156 (84.8)   147 (77.0) 142 (75.9)  
   3 rs2886161 GG 16 (9.7) 15 (7.9) 0.578 27 (14.4) 17 (9.4) 0.0656
   AG 59 (35.8) 91 (47.9)   75 (40.1) 67 (37.0)  
   AA 90 (54.5) 84 (44.2)   85 (45.5) 97 (53.6)  
   4 rs1806649 AA 14 (8.5) 15 (7.9) 0.819 9 (4.8) 23 (12.7) 0.011
   AG 65 (39.4) 80 (42.1)   60 (32.3) 61 (33.7) (0.121)
   GG 86 (52.1) 95 (50.0)   117 (62.9) 97 (53.6)  
   5 rs2001350 GG 1 (0.6) 0 (0.0) 0.016 4 (2.1) 0 (0.0) 0.663
   AG 35 (21.2) 23 (12.1) (0.224) 28 (14.7) 39 (20.9)  
   AA 129 (78.2) 167 (87.9)   158 (83.2) 148 (79.1)  
   6 rs10183914 AA 14 (8.5) 25 (13.2) 0.111 20 (10.8) 28 (15.0) 0.254
   AG 81 (49.1) 89 (46.8)   73 (39.2) 73 (39.0)  
   GG 70 (42.4) 76 (40.0)   93 (50.0) 86 (46.0)  
   7 rs2706110 AA 6 (3.7) 4 (2.1) 0.238 7 (4.0) 1 (0.6) 0.780
   AG 48 (29.3) 40 (21.1)   45 (25.4) 53 (30.6)  
   GG 110 (67.1) 146 (76.8)   125 (70.6) 119 (68.8)  
   8 rs13035806 TT 2 (1.2) 2 (1.1) 0.796 2 (1.2) 0 (0.0) 0.323
   CT 29 (17.7) 27 (14.2)   28 (16.7) 27 (14.9)  
   CC 133 (81.1) 161 (84.7)   138 (82.1) 154 (85.1)  
KEAP1         
   1 rs1048287 CC 1 (0.6) 2 (1.1) 0.589 --- --- ---
   CT 35 (21.5) 42 (22.1)   --- ---  
   TT 127 (77.9) 146 (76.8)   --- ---  
   2 rs11085735 TT 2 (1.2) 2 (1.1) 0.737 --- --- ---
   GT 19 (11.7) 24 (12.8)   --- ---  
   GG 142 (87.0) 162 (86.1)   --- ---  
   3 rs1048290 GG 22 (13.5) 31 (16.3) 0.372 --- --- ---
   CG 77 (47.2) 89 (46.9)   --- ---  
   CC 64 (39.3) 70 (36.8)   --- ---  
  1. Data are presented as absolute numbers (percentages). 1For SNP locations see table 2. 2Genotype information available for most cases as specified by the n numbers. 3p-values were calculated using an additive logistic regression model including statistically relevant covariates.