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Table 2 Haplotype association analysis between caspase-1 gene and AD

From: Caspase-1 genetic variation is not associated with Alzheimer's disease risk

Haplotype block

Haplotype frequency

AD, control frequency

p-value

GAA

0.531

0.521, 0.540

0.32

GAG

0.319

0.324, 0.315

0.60

ACG

0.088

0.094, 0.082

0.29

AAG

0.062

0.061, 0.063

0.83

  1. Haplotype block consists of SNPs: rs501192, rs556205 and rs530537; rare haplotypes (total frequency < 0.05) were excluded from the analysis; p-values were not corrected for multiple comparisons.