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Table 4 Genotype frequencies of IL-1RN VNTR, comparison of 205 athletes and 458 non-athlete controls.

From: Variable number of tandem repeat polymorphisms of the interleukin-1 receptor antagonist gene IL-1RN: a novel association with the athlete status

 

All subjects

(n = 663)

Athletes

(n = 205)

Controls

(n = 458)

OR

(95% CI)

P-value

Athletes versus controls

IL-1RN VNTR genotype

    

< 0.001

1/1

358 (54.0%)

90 (43.9%)

268 (58.5%)

0.55 (0.40-0.77)

< 0.001

1/2

205 (30.9%)

84 (41.0%)

121 (26.4%)

1.93 (1.37-2.74)

< 0.001

1/3

23 (3.5%)

3 (1.5%)

20 (4.4%)

0.33 (0.10-1.11)

0.067

2/2

64 (9.7%)

22 (10.7%)

42 (9.2%)

1.19 (0.69-2.05)

0.529

2/3

7 (1.1%)

4 (2.0%)

3 (0.7%)

3.02 (0.67-13.6)

0.211

1/2 and 2/2 and 2/3 and 2/4

278 (41.9%)

110 (53.7%)

168 (36.7%)

2.00 (1.43-2.79)

< 0.001

1/3 and 2/3 and 3/3

32 (4.8%)

8 (3.9%)

24 (5.2%)

0.73 (0.32-1.66)

0.458

IL-1RN VNTR allele

    

0.001

Allele 1

946 (71.3%)

268 (65.4%)

678 (74.0%)

0.66 (0.52-0.85)

0.001

Allele 2

342 (25.8%)

132 (32.2%)

210 (22.9%)

1.60 (1.23-2.07)

< 0.001

Allele 3

34 (2.6%)

9 (2.2%)

25 (2.7%)

0.80 (0.37-1.73)

0.570