| All subjects (n = 663) | Athletes (n = 205) | Controls (n = 458) | OR (95% CI) | P-value Athletes versus controls |
---|---|---|---|---|---|
IL-1RN VNTR genotype | Â | Â | Â | Â | < 0.001 |
1/1 | 358 (54.0%) | 90 (43.9%) | 268 (58.5%) | 0.55 (0.40-0.77) | < 0.001 |
1/2 | 205 (30.9%) | 84 (41.0%) | 121 (26.4%) | 1.93 (1.37-2.74) | < 0.001 |
1/3 | 23 (3.5%) | 3 (1.5%) | 20 (4.4%) | 0.33 (0.10-1.11) | 0.067 |
2/2 | 64 (9.7%) | 22 (10.7%) | 42 (9.2%) | 1.19 (0.69-2.05) | 0.529 |
2/3 | 7 (1.1%) | 4 (2.0%) | 3 (0.7%) | 3.02 (0.67-13.6) | 0.211 |
1/2 and 2/2 and 2/3 and 2/4 | 278 (41.9%) | 110 (53.7%) | 168 (36.7%) | 2.00 (1.43-2.79) | < 0.001 |
1/3 and 2/3 and 3/3 | 32 (4.8%) | 8 (3.9%) | 24 (5.2%) | 0.73 (0.32-1.66) | 0.458 |
IL-1RN VNTR allele | Â | Â | Â | Â | 0.001 |
Allele 1 | 946 (71.3%) | 268 (65.4%) | 678 (74.0%) | 0.66 (0.52-0.85) | 0.001 |
Allele 2 | 342 (25.8%) | 132 (32.2%) | 210 (22.9%) | 1.60 (1.23-2.07) | < 0.001 |
Allele 3 | 34 (2.6%) | 9 (2.2%) | 25 (2.7%) | 0.80 (0.37-1.73) | 0.570 |