Fibrinogen beta variants confer protection against coronary artery disease in a Greek case-control study

BMC Medical Genetics

Table 5 Frequencies, ORs and 95% CIs for CAD in relation to the most frequent haplotypes.

Haplotype	Controls (%)	Cases (%)	OR;95%CI	P-value	adjusted OR;95%CI^a	adjusted P-value^a
FGA-H1	33.00	38.13	referent		referent
FGA-H2	28.88	26.25	0.80;0.60-1.05	0.104	0.81;0.59-1.11	0.186
FGA-H3	21.10	20.27	0.84;0.62-1.14	0.256	0.75;0.53-1.07	0.111
FGA-H4	16.20	14.65	0.78;0.55-1.11	0.164	0.84;0.56-1.26	0.396
FGG-H1	48.84	45.16	referent		referent
FGG-H2	32.78	32.81	1.06;0.83-1.36	0.638	1.13;0.86-1.50	0.387
FGG-H3	16.55	20.78	1.31;0.97-1.77	0.078	1.31;0.93-1.87	0.122
FGB-H1	72.34	75.37	referent		referent
FGB-H2	21.84	20.77	0.92;0.71-1.20	0.547	0.89;0.65-1.21	0.463
FGA-FGG-H1	26.00	23.97	referent		referent
FGA-FGG-H2	19.50	18.31	1.05;0.76-1.45	0.771	0.94;0.65-1.37	0.755
FGA-FGG-H3	15.71	20.08	1.42;1.02-1.98	0.040	1.38;0.94-2.02	0.098
FGA-FGG-H4	15.85	14.60	1.03;0.71-1.48	0.893	1.09;0.72-1.66	0.665
FGA-FGG-H5	14.03	15.28	1.22;0.86-1.75	0.264	1.21;0.79-1.84	0.381

^a adjustment for age, sex and the presence of hypercholesterolemia, hypertension, diabetes and smoking

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