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Table 5 The genotype frequencies of LEPR polymorphism

From: Leptin receptor (LEPR) SNP polymorphisms in HELLP syndrome patients determined by quantitative real-time PCR and melting curve analysis

  

Allele frequency

HW

LEPR SNP

% tested

Major

Minor

P-value

c. 326 A>G

100

A: 0.753

G: 0.247

0.06127

c. 668 A>G

100

A: 0.57

G: 0.43

0.06276

c. 1968 G>C

100

G: 0.823

C: 0.177

0.82495

c. 3024 A>G

100

G: 0.652

A: 0.348

0.68796

  1. HW = Hardy-Weinberg equilibrium
  2. lag out condition: 0.5 < Sample Missing, 0.1 < SNP Missing, 0.05 > SNP MAF, 0.05/4 = 0.0125 > SNP HWE p-value, with multiple correction
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BMC Medical Genetics

ISSN: 1471-2350

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