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Table 3 Allele and genotype frequencies of SNPs in DRD2 and their association status with AD

From: Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: a preliminary study

SNPs

Genotypes

Statistics

Alleles

Statistics

Power (*G %)

-141C Ins/Del

Ins/Ins

Ins/Del

Del/Del

 

Ins

Del

  

AD

0.61

0.32

0.07

χ 2 = 11.0, P < 0.01

0.77

0.23

χ 2 = 4.3, P < 0.05

62

Controls

0.57

0.16

0.27

 

0.65

0.35

  

TaqI B

GG

GA

AA

 

G

A

  

AD

0.07

0.37

0.56

χ2 = 0.11, P = 0.94

0.25

0.75

χ2 = 0.12, P = 0.72

6

Controls

0.11

0.31

0.58

 

0.27

0.73

  

TaqI A

A1A1

A1A2

A2A2

 

A1

A2

  

AD

0.04

0.45

0.51

Fisher's exact test P < 0.05

0.27

0.73

Fisher's exact test p = 0.08

16

Controls

0.07

0.30

0.63

 

0.22

0.78

  
  1. *G: the power of SNP to detect association, calculated using PAWE software