Figure 1
From: A novel DSPPmutation causes dentinogenesis imperfecta type II in a large Mongolian family
Pedigree structure of a Mongolian family affected by dentinogenesis imperfecta type II (DGI-II). Affected males and females are indicated by filled squares and circles, respectively. Normal individuals are shown as empty symbols. The proband is IV5. Two-point linkage analysis was conducted using five polymorphic microsatellite markers (GATA62A11, D3S564, D4S1317, D4S3132 and D4S1563) in region 4q21.3. Genotype results are shown under each symbol. Note that haplotype 3-2-3-4-1 co-segregates with affected individuals, suggesting linkage of DSPP to DGI-II in this family.