Figure 2

Simulation of allele and genotype frequencies of the βS polymorphism for 50 generations in Hausa and Massalit villages. Simulation is based on actual genotype data and with projections based on fitness equation as described in the materials and methods section. Figure 2(A): Simulation for HbA and Hb S allele frequencies over 50 generations in Hausa. Figure 2(c): Simulation for HbA and Hb S alleles frequencies over 50 generations in Massalit. Figure 2(B): Simulation for HbA and Hb S genotypes frequencies over 50 generations in Hausa. Figure 2(D): Simulation for HbA and Hb S genotypes frequencies over 50 generations in Massalit. All simulations are based on fitness measures as calculated from genotypes of two generations.