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Table 4 Odds ratios of AD for DBH -1021TT+TC vs CC in certain subsets

From: The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project

Subset

Adjusted* odds ratios of AD (95% CI, p)

 

All

North Europe

North Spain

All

1.2 (1.06-1.4, 0.005)

1.2 (1.05-1.4, 0.01)

1.3 (0.97-1.7, 0.08)

Men

1.6 (1.2-2.0, 0.0002)

1.7 (1.3-2.2, 0.0002)

1.5 (0.9-2.55, 0.12)

All < 75 years

1.6 (1.2-2.2, 0.001)

1.55 (1.1-2.2, 0.02)

1.8 (1.04-3.0, 0.03)

Men < 75 years

2.2 (1.4-3.3, 0.0004)

2.2 (1.3-3.8, 0.002)

1.9 (0.8-4.4, 0.12)

  1. AD = Alzheimer's disease, DBH = dopamine β-hydroxylase, CI = confidence interval.
  2. * All analyses controlled for centre, age, sex and genotype of apolipoprotein E ε4.
  3. Results in bold are significant at p < 0.05.