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Table 3 Odds ratios of AD for DBH -1021TT+TC vs CC, stratified by sex and by age

From: The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project

Subset

Adjusted* odds ratios of AD

(95% CI, p)

Men

1.6 (1.2-2.0, 0.0002)

Women

1.05 (0.9-1.2, 0.60)

All < 75 years

1.6 (1.2-2.2, 0.001)

All > 75 years

1.06 (0.9-1.3, 0.47)

Men < 75 years

2.2 (1.4-3.3, 0.0004)

Men > 75 years

1.35 (0.98-1.8, 0.06)

Women < 75 years

1.3 (0.9-1.9, 0.24)

Women > 75 years

0.95 (0.8-1.2, 0.66)

  1. AD = Alzheimer's disease, DBH = dopamine β-hydroxylase, CI = confidence interval.
  2. * All analyses controlled for centre, age, sex and genotype of apolipoprotein E ε4.
  3. Results in bold are significant at p < 0.05.