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Table 2 Odds ratios (OR) for angiographic CAD according to the rs2259816 genotype.

From: Effect of the rs2259816 polymorphism in the HNF1A gene on circulating levels of c-reactive protein and coronary artery disease (the ludwigshafen risk and cardiovascular health study)

rs2259816 genotype

Model 1 OR (95% CI)

P

Model 2 OR (95% CI)

P

Model 3 OR (95% CI)

P

CC (n = 1264)

1.0reference

 

1.0reference

 

1.0reference

 

CA1 (n = 1395)

1.005 (0.835 - 1.210)

0.957

1.013 (0.832 - 1.232)

0.900

1.038 (0.847 - 1.272)

0.717

AA1 (n = 454)

1.050 (0.807 - 1.367)

0.716

1.045 (0.792 - 1.380)

0.755

1.083 (0.811 - 1.445)

0.590

CC vs CA vs AA

1.020 (0.901 - 1.154)

0.755

1.020 (0.895 - 1.162)

0.766

1.040 (0.908 - 1.191)

0.572

CC vs CA + AA

1.016 (0.835 - 1.209)

0.860

1.021 (0.848 - 1.227)

0.829

1.049 (0.866 - 1.270)

0.626

CC + CA vs AA

1.047 (0.820 - 1.338)

0.712

1.038 (0.802 - 1.344)

0.775

1.061 (0.812 - 1.387)

0.664

  1. 1Genotypes treated as categorical variables and compared to the reference category.
  2. Model 1: unadjusted.
  3. Model 2: adjusted for age, and gender.
  4. Model 3: in addition adjusted for type 2 diabetes, body mass index, smoking, hypertension, LDL-C, HDL-C, TG