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Table 1 Baseline characteristics and risk factors in patients with angiographically proven CAD as compared to controls without CAD.

From: Effect of the rs2259816 polymorphism in the HNF1A gene on circulating levels of c-reactive protein and coronary artery disease (the ludwigshafen risk and cardiovascular health study)

 

No CAD

CAD

P 1

 

(n = 665)

(n = 2448)

 

Age (years) means ± SD

58 ± 12

64 ± 10

< 0.001

Body mass index (kg/m2) means ± SD

27 ± 4

28 ± 4

n.s.

Smoker (former and current)

324 (49%)

1675 (68%)

 

Diabetes mellitus

125 (19%)

872 (36%)

 

Systemic Hypertension

417 (63%)

1841 (75%)

 

Systolic blood pressure (mm Hg) means ± SD

136 ± 22

142 ± 24

0.0143

Diastolic blood pressure (mm Hg) means ± SD

80 ± 11

81 ± 11

n.s.

Fasting blood glucose (mg/dl) means ± SD

105 ± 28

116 ± 37

< 0.001

LDL-C(mg/dl) means ± SD

120 ± 31

116 ± 35

0.0014

HDL-C (mg/dl) means ± SD

43 ± 12

38 ± 10

< 0.0014

Triglycerides (mg/dl)median (25th and 75th percentile)

132

(97-194)

150

(113-202)

< 0.001

  1. 1Analysis of variance or logistic regression, respectively, adjusted for age and gender.2Analysis of variance adjusted for gender only.3Analysis of variance additionally adjusted for use of lipid-lowering drugs, beta blockers, ACE inhibitors, AT1 receptor antagonists, calcium channel blockers and diuretics.
  2. 4Analysis of variance additionally adjusted for use of lipid-lowering drugs.