Linkage analysis of obesity phenotypes in pre- and post-menopausal women from a United States mid-western population

Table 4 Bivariate multivariable-adjusted^a multipoint linkage (LOD ≥ 3.0) at chromosomal regions with obesity-related traits among pre-menopausal women.

Position	Trait^b	Peak LOD score	Marker	Peak LOD position (cM)
2p23	BMI-HC	3.30	D2S165	47.90
2p23	BMI-WHR	3.17	D2S165	48.47
3p26	BMI-HC	3.65	D3S1304	14.05
3p26	BMI-WC	3.00	D3S1304	14.83
11q22	BMI-HC	3.14	D11S898	104.45
13q13	BMI-HC	3.59	D13S218	40.88
13q13	HC-WHR	3.01	D13S218	41.47
13q14	BMI-HC	3.59	D13S263	40.88
13q14	HC-WHR	3.01	D13S263	41.47
13q14	WC-WHR	3.00	D13S263	42.66
13q14	BMI-WHR	3.28	D13S263	43.25

^aAdjusted for age, parity, education, smoking, physical activity, and oophorectomy. BMI was included in the models of waist circumference and WHR, and of hip circumference and WHR
^bBMI, body mass index; WHR, waist to hip ratio; WC, waist circumference; HC, hip circumference.

ISSN: 1471-2350