From: Chromosomal abnormalities in spontaneous abortion after assisted reproductive treatment
 | Control group (n = 128) | Conventional IVF group (n = 114) | ICSI group (n = 140) | p-value |
---|---|---|---|---|
Maternal age (yr) | 34.52 ± 4.13 | 35.70 ± 3.97 | 35.49 ± 4.23 | 0.055 |
Paternal age (yr) | 36.05 ± 4.34a | 37.43 ± 4.39a,b | 38.07 ± 5.40b | 0.002 |
Maternal BMI | 21.13 ± 2.49 | 21.16 ± 3.04 | 21.73 ± 2.93 | 0.162 |
Semen analysis | ||||
   Volume (ml) | 2.91 ± 1.59 | 2.83 ± 1.18 | 2.57 ± 1.42 | 0.167 |
   Count (x106/ml) | 91.85 ± 43.72 a | 93.62 ± 58.41 a | 66.48 ± 66.50 b | < 0.001 |
   Morphology, strict | 6.14 ± 2.36 a | 6.68 ± 2.86 a | 4.25 ± 3.57 b | < 0.001 |
   Motility | 47.90 ± 15.46 a | 48.56 ± 16.75 a | 37.99 ± 21.11 b | < 0.001 |
Hormonal profile | ||||
   Basal FSH (u/ml) | 7.17 ± 2.76 | 7.49 ± 5.08 | 7.28 ± 3.58 | 0.886 |
   Basal LH (u/ml) | 4.18 ± 4.01 | 3.06 ± 1.71 | 3.83 ± 3.08 | 0.127 |
   Basal E2 (pg/ml) | 28.25 ± 14.29 | 28.41 ± 21.74 | 30.44 ± 24.19 | 0.729 |
Fetal gestational age at D&E (days) | 59.66 ± 8.23 | 61.00 ± 7.51 | 60.98 ± 7.77 | 0.300 |
Previous pregnancy status (n) | ||||
   Parity | 1.63 ± 1.47a | 1.32 ± 1.51a,b | 0.99 ± 1.18b | 0.001 |
   Abortion | 1.11 ± 1.21a | 0.61 ± 0.98b | 0.49 ± 0.66b | < 0.001 |