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Table 5 Estimated haplotype frequencies and association with sarcoidosis

From: Genetic variants in mannose receptor gene (MRC1) confer susceptibility to increased risk of sarcoidosis

Haplotype

controls (%)*

cases (%)*

total (%)*

haplotype-specific score

simulated P †

rs2477631-rs2477664

     

A-A

48.6

48.4

48.6

-0.171

0.863

C-T

42.7

42.9

42.8

0.089

0.929

rs692527-rs1926736

     

A-A

46.0

41.4

44.6

-1.601

0.111

A-G

9.8

9.5

9.7

-0.428

0.667

G-G

42.4

45.2

43.2

1.074

0.279

rs554995-rs554313-rs691005

    

G-G-T

30.6

30.6

30.6

0.098

0.916

A-G-C

27.7

29.4

28.1

0.741

0.452

G-A-T

29.3

36.2

34.7

2.220

0.028

  1. *Minimum haplortpe frequency was 0.05 for which haplotypes were scored in the model.
  2. †adjusted by sex and age