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Table 4 Association of rs1805081 in NPC1 Gene with CHD classified by smoking

From: Interaction of functional NPC1gene Polymorphism with smoking on coronary heart disease

  

non-smoking

smoking

Models

 

ORs(95% CI)

PValue

ORs(95% CI)

PValue

GG vs. AG+AA

Crude

0.773(0.441 to 1.357)

0.3703

0.606(0.351 to 1.047)

0.0727

 

Adjusted

0.766(0.423 to 1.386)

0.3537

0.552(0.311 to 0.979)

0.0421

GG vs. AG vs. AA

Crude

0.954(0.759 to 1.198)

0.6839

0.810(0.652 to 1.006)

0.0571

 

Adjusted

0.909(0.714 to 1.158)

0.441

0.778(0.620 to 0.976)

0.0301

GG+AG vs. AA

Crude

0.994(0.744 to 1.328)

0.9672

0.817(0.625 to 1.068)

0.1391

 

Adjusted

0.846(0.622 to 1.151)

0.2868

0.804(0.607 to 1.065)

0.1277

  1. ORs and 95% CIs were computed with the use of binary logistic regression analyses. Adjusted ORs were stratified by age, sex, body mass index, hypertension history, cigarette smoking, and Diabetes mellitus history.