Figure 4From: A prevalent mutation with founder effect in Spanish Recessive Dystrophic Epidermolysis Bullosa families Some pedigrees of Spanish cases of DEB are shown as an example. The existence of complete two-generation pedigrees in DEB patients allowed construction of different haplotypes throughout the COL7A1 gene. The haplotypes are boxed. Symbols are encoded as follows: black, DEB patients; white and black, carrying recessive mutationsBack to article page