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Table 3 Regression analysis between SNPs and haplotypes of CACNG6 in all subjects

From: Association of CACNG6 polymorphisms with aspirin-intolerance asthmatics in a Korean population

SNP or Haplotype Position C/C C/R R/R Pa Pb Pc
rs251850 Promoter 397 (9.41 ± 13.26) 180 (8.48 ± 12.24) 15 (13.60 ± 21.54) 0.91 0.57 0.19
rs4806481 Intron 153 (10.09 ± 13.84) 308 (9.34 ± 13.47) 129 (8.07 ± 11.90) 0.25 0.38 0.32
rs158196 Intron 251 (9.19 ± 13.69) 265 (8.81 ± 12.70) 76 (10.85 ± 13.47) 0.75 0.79 0.29
rs158199 Intron 349 (8.92 ± 12.97) 204 (9.63 ± 13.63) 39 (9.97 ± 13.55) 0.75 0.78 0.81
rs192808 Intron 529 (8.81 ± 12.99) 60 (12.35 ± 13.94) 3 (21.67 ± 28.36) 0.006 0.01 0.06
CACNG6_BL1_ht1   259 (9.55 ± 13.60) 271 (9.11 ± 12.76) 62 (8.45 ± 13.77) 0.64 0.68 0.73
CACNG6_BL1_ht2   382 (9.19 ± 13.48) 178 (9.05 ± 12.56) 32 (10.72 ± 13.99) 0.98 0.82 0.59
CACNG6_BL1_ht3   421 (9.34 ± 13.30) 159 (8.41 ± 11.88) 12 (16.39 ± 23.38) 0.92 0.64 0.07
CACNG6_BL1_ht4   481 (9.40 ± 13.60) 104 (8.67 ± 11.80) 7 (6.14 ± 2.97) 0.5 0.56 0.57
CACNG6_BL1_ht5   493 (9.52 ± 13.23) 96 (7.91 ± 13.32) 3 (4.67 ± 2.31) 0.32 0.33 0.66
CACNG6_BL1_ht6   530 (8.83 ± 12.99) 60 (12.90 ± 14.91) 2 (5.50 ± 6.36) 0.03 0.02 0.69
rs450227 Intron 426 (9.18 ± 13.11) 157 (9.38 ± 13.56) 9 (9.33 ± 13.76) 0.89 0.91 0.87
rs2291068 Exon 378 (9.17 ± 13.17) 194 (9.40 ± 13.14) 20 (8.72 ± 15.41) 0.69 0.79 0.61
rs459247 Exon 150 (11.12 ± 15.52) 290 (8.74 ± 11.28) 152 (8.32 ± 14.07) 0.12 0.06 0.48
CACNG6_BL2_ht1   153 (11.09 ± 15.38) 290 (8.70 ± 11.28) 149 (8.37 ± 14.19) 0.12 0.06 0.50
CACNG6_BL2_ht2   301 (8.17 ± 12.70) 240 (10.55 ± 13.87) 51 (9.34 ± 12.78) 0.09 0.03 0.97
CACNG6_BL2_ht3   442 (9.37 ± 13.28) 145 (8.72 ± 12.92) 5 (11.80 ± 18.75) 0.51 0.44 0.75
CACNG6_BL2_ht4   515 (9.12 ± 13.08) 76 (9.99 ± 14.29) 1 (8.00) 0.86 0.83 0.78
  1. C/C, common allele/common allele; C/R, common allele/rare allele; R/R, rare allele/rare allele;
  2. Pa, P-values of co-dominant model; Pb, dominant model; Pc, recessive model.