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Table 3 Regression analysis between SNPs and haplotypes of CACNG6 in all subjects

From: Association of CACNG6 polymorphisms with aspirin-intolerance asthmatics in a Korean population

SNP or Haplotype

Position

C/C

C/R

R/R

Pa

Pb

Pc

rs251850

Promoter

397 (9.41 ± 13.26)

180 (8.48 ± 12.24)

15 (13.60 ± 21.54)

0.91

0.57

0.19

rs4806481

Intron

153 (10.09 ± 13.84)

308 (9.34 ± 13.47)

129 (8.07 ± 11.90)

0.25

0.38

0.32

rs158196

Intron

251 (9.19 ± 13.69)

265 (8.81 ± 12.70)

76 (10.85 ± 13.47)

0.75

0.79

0.29

rs158199

Intron

349 (8.92 ± 12.97)

204 (9.63 ± 13.63)

39 (9.97 ± 13.55)

0.75

0.78

0.81

rs192808

Intron

529 (8.81 ± 12.99)

60 (12.35 ± 13.94)

3 (21.67 ± 28.36)

0.006

0.01

0.06

CACNG6_BL1_ht1

 

259 (9.55 ± 13.60)

271 (9.11 ± 12.76)

62 (8.45 ± 13.77)

0.64

0.68

0.73

CACNG6_BL1_ht2

 

382 (9.19 ± 13.48)

178 (9.05 ± 12.56)

32 (10.72 ± 13.99)

0.98

0.82

0.59

CACNG6_BL1_ht3

 

421 (9.34 ± 13.30)

159 (8.41 ± 11.88)

12 (16.39 ± 23.38)

0.92

0.64

0.07

CACNG6_BL1_ht4

 

481 (9.40 ± 13.60)

104 (8.67 ± 11.80)

7 (6.14 ± 2.97)

0.5

0.56

0.57

CACNG6_BL1_ht5

 

493 (9.52 ± 13.23)

96 (7.91 ± 13.32)

3 (4.67 ± 2.31)

0.32

0.33

0.66

CACNG6_BL1_ht6

 

530 (8.83 ± 12.99)

60 (12.90 ± 14.91)

2 (5.50 ± 6.36)

0.03

0.02

0.69

rs450227

Intron

426 (9.18 ± 13.11)

157 (9.38 ± 13.56)

9 (9.33 ± 13.76)

0.89

0.91

0.87

rs2291068

Exon

378 (9.17 ± 13.17)

194 (9.40 ± 13.14)

20 (8.72 ± 15.41)

0.69

0.79

0.61

rs459247

Exon

150 (11.12 ± 15.52)

290 (8.74 ± 11.28)

152 (8.32 ± 14.07)

0.12

0.06

0.48

CACNG6_BL2_ht1

 

153 (11.09 ± 15.38)

290 (8.70 ± 11.28)

149 (8.37 ± 14.19)

0.12

0.06

0.50

CACNG6_BL2_ht2

 

301 (8.17 ± 12.70)

240 (10.55 ± 13.87)

51 (9.34 ± 12.78)

0.09

0.03

0.97

CACNG6_BL2_ht3

 

442 (9.37 ± 13.28)

145 (8.72 ± 12.92)

5 (11.80 ± 18.75)

0.51

0.44

0.75

CACNG6_BL2_ht4

 

515 (9.12 ± 13.08)

76 (9.99 ± 14.29)

1 (8.00)

0.86

0.83

0.78

  1. C/C, common allele/common allele; C/R, common allele/rare allele; R/R, rare allele/rare allele;
  2. Pa, P-values of co-dominant model; Pb, dominant model; Pc, recessive model.