Skip to main content

Table 2 Risk of dyspepsia according to GNB3 genotypes

From: The G-Protein β3 subunit 825 TT genotype is associated with epigastric pain syndrome-like dyspepsia

 

FD, total

(n = 68)

 

EPS

(n = 43)1

 

PDS

(n = 40)1

 

EPS excluding PDS

(n = 28)

 
 

OR

(95%CI)

P

OR

(95%CI)

P

OR

(95%CI)

P

OR

(95%CI)

P

GNB3 genotype

            

CC

1

reference

 

1

reference

 

1

reference

 

1

reference

 

CT

0.85

(0.45-1.59)

0.605

1.03

(0.44-2.45)

0.943

0.70

(0.33-1.45)

0.335

1.31

(0.40-4.23)

0.657

TT

1.18

(0.61-2. 30)

0.618

2.05

(0.87-4.83)

0.102

0.54

(0.22-1.34)

0.185

3.32

(1.07-10.28)

0.037

Dominant model

            

TT+CT vs. CC

0.97

(0.54-1.72)

0.910

1.39

(0.63-3.06)

0.414

0.64

(0.32-1.28)

0.207

2.03

(0.69-5.94)

0.196

Recessive model

            

TT vs. CT+CC

1.32

(0.77-2.45)

0.310

2.00

(1.07-3.76)

0.030

0.68

(0.31-1.51)

0.342

2.73

(1.23-5.91)

0.008

  1. 1Fifteen subjects simultaneously had EPS- and PDS-like symptoms.
  2. FD, functional dyspepsia; EPS, epigastric pain syndrome; PDS, postprandial distress syndrome;
  3. OR, sex- and age-adjusted odds ratio, vs. 912 controls, by a multiple logistic regression model; CI, confidence interval.
Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us