|  | Total | Male | Female | ||||||
---|---|---|---|---|---|---|---|---|---|---|
SNPs | Genotype | NT(n = 495) | EH(n = 490) | P | NT(n = 293) | EH(n = 316) | P | NT(n = 202) | EH(n = 174) | P |
T1880C | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Additive | TT | 2(0.4%) | 3(0.6%) | 0.44 | 2(0.7%) | 3(0.9%) | 0.65 | 0(0.0%) | 0(0.0%) | 0.38 |
 | TC | 48(9.7%) | 37(7.6%) |  | 29(9.9%) | 25(7.9%) |  | 19(9.4%) | 12(6.9%) |  |
 | CC | 445(89.9%) | 450(91.8%) |  | 262(89.4%) | 288(91.1%) |  | 183(90.6%) | 162(93.1%) |  |
Dominant | TT + TC | 50(10.1%) | 40(8.9%) | 0.29 | 31(10.6%) | 28(8.9%) | 0.47 | 19(9.4%) | 12(6.9%) | 0.39 |
 | CC | 445(89.9%) | 450(91.1%) |  | 262(89.4%) | 288(91.1%) |  | 183(90.6%) | 162(93.1%) |  |
 | OR |  | 1.26 |  |  | 1.22 |  |  | 1.40 |  |
 | 95% CI |  | 0.82-1.96 |  |  | 0.71-2.08 |  |  | 0.66-2.98 |  |
Recessive | CC + TC | 493(99.6%) | 487(99.4%) | 0.65 | 291(99.3%) | 313(99.1%) | 0.72 | 202(100%) | 174(100%) | - |
 | TT | 2(0.4%) | 3(0.6%) |  | 2(0.7%) | 3(0.9%) |  | 0 | 0 |  |
 | OR |  | 1.52 |  |  | 1.40 |  |  |  | - |
 | 95% CI |  | 0.25-9.13 |  |  | 0.23-8.41 |  |  | - |  |
Allele | T | 52(5.3%) | 43(4.4%) | 0.37 | 33(5.6%) | 31(4.9%) | 0.57 | 19(4.7%) | 12(3.4%) | 0.39 |
 | C | 938(94.7%) | 937(95.6%) |  | 553(94.4%) | 601(95.1%) |  | 385(95.3%) | 336(96.6%) |  |
 | OR |  | 1.21 |  |  | 1.16 |  |  | 0.38 |  |
 | 95% CI |  | 0.80-1.83 |  |  | 0.70-1.91 |  |  | 0.66-2.89 |  |
C602A | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Additive | CC | 0(0.0%) | 5(1.0%) | 0.005 | 0(0.0%) | 4(1.3%) | 0.01 | 0(0.0%) | 1(0.6%) | 0.33 |
 | CA | 21(4.2%) | 38(7.8%) |  | 11(3.8%) | 25(7.9%) |  | 10(5.0%) | 13(10.6%) |  |
 | AA | 474(95.8%) | 447(91.2%) |  | 282(96.2%) | 287(90.8%) |  | 192(95.0%) | 160(92.0%) |  |
Dominant | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | CC + CA | 21(4.2%) | 43(8.8%) | 0.004 | 11(3.8%) | 29(9.2%) | 0.007 | 10(5.0%) | 14(8.0%) | 0.22 |
 | AA | 474(95.8%) | 447(91.2%) |  | 282(96.2%) | 287(90.8%) |  | 192(95.0%) | 160(92.0%) |  |
 | OR |  | 0.461 |  |  | 0.386 |  |  | 0.595 |  |
 | 95% CI |  | 0.269-0.788 |  |  | 0.189-0.788 |  |  | 0.257-1.376 |  |
Recessive | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | AA + CA | 495(100%) | 485(99.0%) | 0.02 | 293(100%) | 312(98.7%) | 0.05 | 202(100%) | 173(99.4%) | 0.28 |
 | CC | 0(0%) | 5(1.0%) |  | 0(0%) | 4(1.3%) |  | 0(0%) | 1(0.6%) |  |
 | OR |  | 1.010 |  |  | 1.013 |  |  | 1.006 |  |
 | 95% CI |  | 1.001-1.019 |  |  | 1.000-1.026 |  |  | 0.994-1.017 |  |
Allele | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | C | 21(2.1%) | 48(4.9%) | 0.001 | 11(1.9%) | 33(5.2%) | 0.002 | 10(2.5%) | 15(4.3%) | 0.16 |
 | A | 969(97.9%) | 932(95.1%) |  | 575(98.1%) | 599(94.8%) |  | 394(97.5%) | 333(95.7%) |  |
 | OR |  | 0.421 |  |  | 0.347 |  |  | 0.563 |  |
 | 95% CI |  | 0.250-708 |  |  | 0.174-0.694 |  |  | 0.250-1.271 |  |
T1559C | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Additive | TT | 43(8.7%) | 33(6.7%) | 0.39 | 30(10.2%) | 16(5.1%) | 0.046 | 13(6.4%) | 17(9.8%) | 0.045 |
 | TC | 200(40.4%) | 191(39.0%) |  | 115(39.2%) | 124(39.2%) |  | 85(42.1%) | 67(38.5%) |  |
 | CC | 252(50.9%) | 266(54.3%) |  | 148(50.5%) | 176(55.7%) |  | 104(51.5%) | 90(51.7%) |  |
Dominant | TT + TC | 243(49.1%) | 224(45.7%) | 0.29 | 145(49.5%) | 140(44.3%) | 0.20 | 98(48.5%) | 84(48.3%) | 0.96 |
 | CC | 252(50.9%) | 266(54.3%) |  | 148(50.5%) | 176(55.7%) |  | 104(51.5%) | 90(51.7%) |  |
 | OR |  | 1.145 |  |  | 1.232 |  |  | 1.010 |  |
 | 95% CI |  | 0.892-1.471 |  |  | 0.895-1.694 |  |  | 0.673-1.515 |  |
Recessive | CC + TC | 452(91.3%) | 457(93.3%) | 0.25 | 263(89.8%) | 300(95.0%) | 0.02 | 189(93.6%) | 157(90.2%) | 0.23 |
 | TT | 43(8.7%) | 33(6.7%) |  | 30(10.2%) | 16(5.0%) |  | 13(6.4%) | 17(9.8%) |  |
 | OR |  | 0.759 |  |  | 0.468 |  |  | 1.574 |  |
 | 95% CI |  | 0.474-1.217 |  |  | 0.249-0.877 |  |  | 0.742-3.341 |  |
Allele | T | 286(28.9%) | 257(26.2%) | 0.19 | 175(30.0%) | 156(24.7%) | 0.05 | 111(27.5%) | 101(29.0%) | 0.63 |
 | C | 704(71.1%) | 723(73.8%) |  | 415(70.0%) | 476(75.3%) |  | 293(72.5%) | 247(71.0%) |  |
 | OR |  | 1.143 |  |  | 1.287 |  |  | 0.926 |  |
 | 95% CI |  | 0.938-1.393 |  |  | 0.999-1.657 |  |  | 0.674-1.274 |  |