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Table 2 SLC2A10 sequence variants and association with PAD in type 2 diabetic patients at baseline.

From: SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10and PAD in type 2 diabetes

# ID Position
(kb)
Function Major/
minor allele
Minor allele frequency
PAD(-) PAD(+)
Allelic p-value
(adjusted*)
Allele OR*
(95% CI)
Genotype distribution**
PAD (-) PAD (+)
Genotypic p-value
(adjusted*)
1 rs2425895 -1.789 5' upstream G/A 0.067 0.056 0.75 (0.83) 0.87 (0.24-3.13) 301:42:2 24:3:0 1.00 (0.82)
2 (TGTGTGTGT)n -0.208 5' upstream 3/2 0.24 0.28 0.54 (0.38) 1.37 (0.68-2.80) 198:128:18 14:11:2 0.72 (0.39)
3 rs2143044 10.341 Intron 1 C/T 0.31 0.44 0.03 (0.03) 2.00 (1.04-3.85) 167:141:35 7:16:4 0.05 (0.04)
4 rs3092412 11.720 Intron 1 A/T 0.39 0.56 0.01 (0.005) 2.51 (1.31-4.81) 130:164:51 4:16:7 0.03 (0.006)
5 rs2235491 15.915 Exon 2
Ala206Thr
G/A 0.074 0.13 0.14 (0.036) 3.03 (1.08-8.55) 296:47:2 21:5:1 0.11 (0.05)
6 rs2425904 18.500 Intron 3 T/C 0.37 0.56 0.007 (0.004) 2.58 (1.34-4.98) 133:167:45 3:18:6 0.006 (0.004)
7 rs2425911 21.843 Intron 4 G/C 0.38 0.56 0.01 (0.005) 2.54 (1.32-4.87) 132:164:49 3:8:6 0.009 (0.005)
8 rs3091904 23.079 Intron 4 C/T 0.38 0.57 0.004 (0.002) 2.83 (1.46-5.46) 136:158:51 3:17:7 0.005 (0.002)
9 rs1059217 26.273 3' UTR C/T 0.37 0.56 0.007 (0.004) 2.58 (1.35-4.95) 185:160:0 9:18:0 0.005 (0.004)
10 rs6066059 29.778 3' downstream C/T 0.37 0.56 0.005 (0.004) 2.61 (1.36-5.00) 138:161:46 3:18:6 0.004 (0.004)
11 rs2179357 32.708 3' downstream C/T 0.33 0.57 2.6 × 10 -4 (< 0.0001) 3.87 (1.97-7.58) 160:143:42 4:15:8 0.001 (< 0.0001)
  1. *P-values and odds ratios were adjusted for covariates including age, sex, duration of diabetes, BMI, triglyceride, total cholesterol, HbA1c, systolic blood pressure and current smoking status.
  2. **Genotype distribution are shown as number (AA: AB: BB); A represents the major allele and B represents the minor allele.
  3. PAD, peripheral artery disease; OR, odds ratio; CI, confidence interval