Table 2 SNPs that replicated in 2 of 3 independent populations
From: Asthma-susceptibility variants identified using probands in case-control and family-based analyses
| Â | Â | Â | Discovery P-values | Rank | Replication P-values | Â | Â | Â | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | Â | Stage 1 | Stage 2 | Â | Â | Â | |
SNP | CHR | BP | CAMP/Illumina | CAMP Trio | CAMP/Illumina | CAMP Trio | CR | FHS | iCAP | Liptak P-value | Nearest RefSeq Gene(s) | Distance From Gene |
rs17572584 | 3 | 144370733 | 4.3E-03 | 0.043 | 2539 | 22513 | 1.4E-03 | 0.011 | 0.052 | 3.5E-05 | CHST2 | 46233 |
rs10489341 | 1 | 207998744 | 8.6E-03 | 0.047 | 4946 | 25122 | 1.9E-03 | 0.023 | 0.056 | 9.2E-05 | TRAF3I | In gene |
rs4653637 | 1 | 223690639 | 2.9E-04 | 0.036 | 189 | 19134 | 0.012 | 0.23 | 6.0E-03 | 7.6E-04 | LBR | In gene |
rs530914 | 11 | 95271804 | 7.8E-03 | 0.031 | 4525 | 16196 | 8.9E-03 | 0.14 | 0.035 | 1.2E-03 | MTMR2 | In gene |
rs10816789 | 9 | 111032330 | 3.5E-03 | 0.030 | 2082 | 16121 | 0.012 | 6.9E-03 | 0.29 | 1.2E-03 | EPB41L | In gene |
rs247052 | 16 | 56524719 | 1.8E-04 | 0.023 | 128 | 12253 | 0.036 | 3.3E-03 | 0.27 | 1.5E-03 | CNGB1 | In gene |
rs1534837 | 14 | 79452778 | 6.5E-04 | 8.8E-03 | 416 | 4617 | 0.047 | 0.059 | 0.037 | 1.9E-03 | NRXN3 | 52265 |
rs714679 | 11 | 44610240 | 2.6E-03 | 7.7E-03 | 1542 | 4053 | 0.032 | 0.15 | 0.028 | 2.9E-03 | CD82 | 12351 |
rs11947034 | 4 | 35448626 | 8.6E-03 | 0.018 | 4963 | 9830 | 0.013 | 0.43 | 0.020 | 4.8E-03 | CENTD1 | 295390 |
rs1152490 | 14 | 55865987 | 3.4E-03 | 0.031 | 2029 | 16236 | 0.045 | 0.039 | 0.21 | 6.6E-03 | PELI2 | 28204 |