Skip to main content

Table 1 Top-ranked SNPs in each Initial Study (CAMP/Illumina or CAMP Trio p-value < 1E-05)

From: Asthma-susceptibility variants identified using probands in case-control and family-based analyses

    Rank Discovery P-values   Stage 1 Stage 2  
SNP CHR BP CAMP/Illumina CAMP Trio CAMP/Illumina CAMP Trio Replication Attempted? CR FHS CAP Liptak P-value*
Top CAMP/Illumina
rs2548659 5 59419643 1 3122 2.07E-07 5.9E-03 yes 0.064 NA 0.15 0.035
rs1588265 5 59405551 2 5000 5.11E-07 9.4E-03 reported in [15] - - - -
rs983280 5 59480894 3 10253 5.71E-07 0.019 yes 0.094 5.7E-03 NA 3.3E-03
rs11778371 8 27375822 4 2947 7.92E-07 5.6E-03 yes 0.29 - - -
rs1544791 5 59474839 5 10852 1.16E-06 0.020 yes/reported in [15] 0.15 - - -
rs684909 11 35843495 6 7849 3.12E-06 0.015 yes 0.99 - - -
rs12725071 1 105022488 7 306415 4.52E-06 0.57 no - - - -
rs17219773 4 61926823 8 11376 4.56E-06 0.021 yes 0.83 - - -
rs12930287 16 64495907 9 228338 4.80E-06 0.42 no - - - -
rs11751990 6 130829469 10 19852 4.97E-06 0.037 yes 0.018 0.81 0.43 0.21
rs2761647 23 95159314 11 NA 5.83E-06 NA no - - - -
rs12724129 1 11880226 12 43354 6.83E-06 0.082 no - - - -
rs7765374 6 87001318 13 8269 7.34E-06 0.015 yes 0.18 - - -
rs2910830 5 59502960 14 16890 7.79E-06 0.032 yes 0.069 0.061 NA 0.016
rs9318942 13 82928515 15 34248 8.72E-06 0.065 no - - - -
Top CAMP Trio
rs1288548 4 186536979 4955 1 8.6E-03 8.7E-07 yes 0.24 - - -
rs261137 5 4414120 1068 2 1.8E-03 1.2E-06 yes 0.053 0.26 0.27 0.049
rs12734338 1 200736346 NA 3 NA 1.7E-06 no - - - -
rs1048329 4 186536752 1637 4 2.8E-03 3.1E-06 yes 0.29 - - -
rs261159 5 4396987 212 5 3.3E-04 3.4E-06 yes 0.086 0.29 0.27 0.072
rs12247820 10 53272196 558 6 9.0E-04 4.2E-06 yes 0.74 - - -
rs12743401 1 200743271 NA 7 NA 4.2E-06 no - - - -
rs261119 5 4418468 4995 8 8.7E-03 4.2E-06 yes 0.44 - - -
rs1039603 5 4345616 309 9 4.8E-04 5.0E-06 yes 0.063 0.32 NA 0.079
rs2777899 17 55187173 828 10 1.4E-03 6.1E-06 yes 0.34 - - -
rs261125 5 4422887 3764 11 6.5E-03 6.6E-06 yes 0.62 - - -
rs13267437 8 4183474 20383 12 0.037 9.5E-06 no - - - -
rs9463425 6 48620994 79984 13 0.15 9.7E-06 no - - - -
  1. *In all available independent populations