Table 4 Meta-Analysis for Association of the four candidate SNPs with generalized Aggressive Periodontitis (gAgP) using the adjusted data from the Greifswald cohort and those published by Schaefer and co-workers [17]
| Â | SNP ID | P Greifswald cohort | n Greifswald cohort | P Schaefer et al. cohort | n Schaefer et al. cohort | P Meta-Analysis | P (BON) Meta-Analysis |
|---|---|---|---|---|---|---|---|
Recessive model | rs2891168 | 3.18 × 10-01 | 468 | 8.80 × 10 -04 | 879 | 1.06 × 10-03 | 4.22 × 10-03 |
|  | rs1333042 | 2.88 × 10-01 | 466 | 1.60 × 10 -03 | 879 | 1.49 × 10-03 | 5.95 × 10-03 |
|  | rs1333048 | 1.18 × 10-01 | 468 | 6.90 × 10 -04 | 876 | 2.49 × 10 -04 | 9.97 × 10 -04 |
|  | rs496892 | 2.20 × 10-01 | 468 | 1.50 × 10-01 | 862 | 5.92 × 10-02 | 2.37 × 10-01 |
Multiplicative model | rs2891168 | 6.44 × 10-02 | 468 | 4.40 × 10-03 | 879 | 6.97 × 10 -04 | 2.79 × 10 -03 |
|  | rs1333042 | 9.51 × 10-02 | 466 | 4.80 × 10-03 | 879 | 1.10 × 10 -03 | 4.42 × 10 -03 |
|  | rs1333048 | 4.22 × 10 -02 | 468 | 2.50 × 10-03 | 876 | 2.73 × 10-04 | 1.09 × 10-03 |
|  | rs496892 | 4.51 × 10 -02 | 468 | 2.40 × 10 -02 | 862 | 2.65 × 10 -03 | 1.06 × 10 -02 |
Dominant model | rs2891168 | 4.73 × 10 -02 | 468 | 1.40 × 10-01 | 879 | 1.82 × 10-02 | 7.28 × 10-02 |
|  | rs1333042 | 9.99 × 10-02 | 466 | 1.20 × 10-01 | 879 | 2.60 × 10-02 | 1.04 × 10-01 |
|  | rs1333048 | 7.95 × 10-02 | 468 | 9.60 × 10-02 | 876 | 1.74 × 10-02 | 6.95 × 10-02 |
|  | rs496892 | 4.94 × 10-02 | 468 | 2.60 × 10-02 | 862 | 3.10 × 10-03 | 1.24 × 10-02 |