Replication of the association of chromosomal region 9p21.3with generalized aggressive periodontitis (gAgP) using an independent case-control cohort

Table 2 Hardy-Weinberg-Equilibrium of all SNPs analyzed in the Greifswald cohort

CHR	SNP ID	HWE TEST	A1	A2	GENO	O(HET)	E(HET)	HW p-value
9	rs2891168	ALL	G	A	108/229/132	0.49	0.50	0.64
9	rs2891168	AFF	G	A	34/69/27	0.53	0.50	0.60
9	rs2891168	UNAFF	G	A	74/160/105	0.47	0.50	0.38
9	rs1333042	ALL	G	A	111/231/125	0.49	0.50	0.85
9	rs1333042	AFF	G	A	35/68/27	0.52	0.50	0.72
9	rs1333042	UNAFF	G	A	76/163/98	0.48	0.50	0.59
9	rs1333048	ALL	C	A	114/229/126	0.49	0.50	0.64
9	rs1333048	AFF	C	A	38/65/27	0.50	0.50	1.00
9	rs1333048	UNAFF	C	A	76/164/99	0.48	0.50	0.66
9	rs496892	ALL	T	C	99/257/113	0.55	0.50	0.04
9	rs496892	AFF	T	C	21/68/41	0.52	0.49	0.48
9	rs496892	UNAFF	T	C	78/189/72	0.56	0.50	0.04

CHR: Chromosome; HWE Test: Test of the respective SNP for Hardy-Weinberg Equilibrium for all analyzed individuals (ALL), cases with gAgP (AFF), and control subjects unaffected by gAgP (UNAFF); A1: Minor allele; A2: Major allele; GENO: Genotype counts: Number of individuals homozygous for the minor allele/Number of heterozygous individuals/Number of individuals homozygous for the major allele; O(HET): Observed heterozygosity; E(HET): Expected heterozygosity; HW p-value: Hardy-Weinberg p-value.

ISSN: 1471-2350